MOLINDONE HYDROCHLORIDE (500 MG)

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H301：Giftig bei Verschlucken.

MOLINDONE HYDROCHLORIDE (500 MG) Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.

• Chemische Eigenschaften

  Light Tan Solid

• Originator

  Moban,Endo,US,1974

• Verwenden

  D2 Dopamine receptor antagonist. MAO inhibitor. Antipsychotic.

• Verwenden

  Antipsychotic;Dopamine receptor antagonist

• Definition

  ChEBI: Molindone hydrochloride is a member of indoles.

• Manufacturing Process

  Diethyl ketone may be reacted with methyl nitrite and that product in turn reacted with cyclohexan-1,3-dione to give 3-ethyl-4,5,6,7-tetrahydro-2- methyl-4-oxoindole.
  3-ethyl-4,5,6,7-tetrahydro-2-methyl-4-oxoindole 14.1 g (0.08 mol), 14.8 g morpholine hydrochloride (0.12 mol), and 3.6 g paraformaldehyde (0.12 mol) were refluxed in 200 ml ethanol for 40 hours. The solution was evaporated to dryness in vacuo on a steam bath and the residue digested with a mixture of 150 ml water and 10 ml 2N HCl. An insoluble residue of unreacted starting material was filtered off. To the acid solution, ammonia water was added dropwise with stirring and the amine crystallized out. It was purified by dissolving in 1N HCl and addition of ammonia, then by 2 crystallizations from benzene followed by 2 crystallizations from isopropanol, to yield 3-ethyl- 4,5,6,7-tetrahydro-2-methyl-4-oxoindole, melting point 180°C to 181°C.

• Trademarks

  Moban (Endo).

• Therapeutic Function

  Antipsychotic

MOLINDONE HYDROCHLORIDE (500 MG) Upstream-Materialien And Downstream Produkte

MOLINDONE HYDROCHLORIDE (500 MG) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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