CCG224406)

CCG224406) Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  CCG-22440 is a Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitor. CCG-224406 had an IC50 for GRK2 of 130 nM, greater than 700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1. G protein-coupled receptors (GPCRs) are central to many physiological processes. Regulation of this superfamily of receptors is controlled by GPCR kinases (GRKs), some of which have been implicated in heart failure.

CCG224406) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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