Acedoben

Bezeichnung:Acedoben

CAS-Nr556-08-1

Englisch Name:p-Acetylamino benzoic acid

CBNumberCB9465840

SummenformelC9H9NO3

Molgewicht179.17

MOL-Datei556-08-1.mol

Synonyma

Acedoben

Acedoben physikalisch-chemischer Eigenschaften

Schmelzpunkt	259-262 °C (dec.)(lit.)
Siedepunkt	311.69°C (rough estimate)
Dichte	1.2822 (rough estimate)
Brechungsindex	1.5600 (estimate)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Powder
pka	pK1: 4.28 (25°C)
Farbe	Off-white to slightly beige
Wasserlöslichkeit	<0.1 g/100 mL at 21 ºC
BRN	390602
Stabilität	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS Datenbank	556-08-1(CAS DataBase Reference)
NIST chemische Informationen	N-(4-Carboxyphenyl)acetic acid amide(556-08-1)
EPA chemische Informationen	Benzoic acid, 4-(acetylamino)- (556-08-1)

Sicherheit

R-Sätze:	36/37/38
S-Sätze:	24/25
WGK Germany	3
TSCA	Yes
HS Code	29242995

Gefahreninformationscode (GHS)

p-Acetylamino benzoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white or off-white powder or crystals
Originator
4-Acetamidobenzoic acid ,ARIAC
Verwenden
immune stimulant (component)
Verwenden
Acedoben is the acetylated derivative of p-aminobenzoic acid (PABA). Acedoben is a metabolite of the anesthetic Benzocaine (B202970).
Definition
ChEBI: A amidobenzoic acid that consists of benzoic acid bearing an acetamido substituent at position 4.
Manufacturing Process
Into a 2 L, 3-necked flask set in a tub and equipped with a stirrer, an air condenser (drying tube), thermometer, was placed 860 ml of water, 43.0 g of MgSO4 and 43.0 g of sodium acetate and heated on water bath. Into heated solution to 70°C stirring 43.0 g of N-p-tolylacetamide were added. Then 136.0 g of KMnO4 by small portions were added at 75°-80°C. The reaction mixture allow to stand for 6 h and stirring was continue till the solution became colorless. Hot solution was filtered and filtrate treated hydrochloric acid to slightly acidic pH. After that 44.0 g (85%) of p-acetoaminobenzoic acid was obtained as white precipitate, melting point 250°C.
Therapeutic Function
Antiviral
Allgemeine Beschreibung
Needles or off-white powder.
Air & Water Reaktionen
Water insoluble.
Reaktivität anzeigen
Simultaneously an amide and a carboxylic acid.
Brandgefahr
Flash point data for p-Acetylamino benzoic acid are not available; however, p-Acetylamino benzoic acid is probably combustible.

p-Acetylamino benzoic acid Upstream-Materialien And Downstream Produkte

Acedoben Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

556-08-1, p-Acetylamino benzoic acid Verwandte Suche:

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