Solvent Green 7

Bezeichnung:Solvent Green 7

CAS-Nr6358-69-6

Englisch Name:Solvent Green 7

CBNumberCB9402700

SummenformelC16H7Na3O10S3

Molgewicht524.39

MOL-Datei6358-69-6.mol

Solvent Green 7 physikalisch-chemischer Eigenschaften

Schmelzpunkt	62-63.5 °C(lit.)
Siedepunkt	171-178 °C10 mm Hg(lit.)
Dichte	2.15
Dampfdruck	0Pa at 25℃
Flammpunkt	250 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	methanol: 0.1 g/mL, clear
Colour Index	59040
Aggregatzustand	Powder
pka	7.3, (at 22℃)
Farbe	yellow
Wasserlöslichkeit	300 g/L (25 ºC)
maximale Wellenlänge (λmax)	403 nm (Buffer pH 4.0); 454 nm (Buffer pH 9.0)
Merck	7954
BRN	4107272
Major Application	Adhesives; agrochemicals; ammonia sensor; carbon dioxide sensor; oxygen sensor; anionic surfactants sensor; measuring the size of the organoclay aggregates; detecting cracks/flaws in metallic surfaces, refrigerant leaking; detergents; correction fluid; highlighters; inks; markers; paints; pencils; toners; chemically amplified resist; color filters; chemiluminescent materials; electrophoretic display (EPD) film materials; electroluminescent displays/materials; fuel cell; lasers; liquid crystal displays; luminescent materials; nanoparticles; papers; photoresist processes; photonic ionic liquids; soils; solar cell; sol–gel materials/processes/thin films; sonophotoluminescence; water tracers; evaluating liquid water flow in wood during drying
Biologische Anwendungen	Antiperspirants; bath preparations; cleansing products; cosmetics; contact lens; hair dyes; hygiene products/soaps; food products; controlled-release system for proteins; drug delivery; in ophthalmology/retinal surgery; sugar sensors (glucose, fructose, lactose, sucrose); as a substrate for measuring acetylcholinesterase (AChE) activity, carbonic anhydrase activity, esterases activity, β-glucuronidase activity, lipase activity, acidic/alkaline phosphatases activity, pyrophosphatase activity, sucrose phosphorylase (SPO) activity, phosphoglucomutase (PGM) activity; treating cancer, infection, immune/autoimmune disease, mastitis, tonsillitis, tuberculosis
LogP	-3.97 at 25℃
CAS Datenbank	6358-69-6(CAS DataBase Reference)
EPA chemische Informationen	C.I. Solvent Green 7 (6358-69-6)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	36/37/38
S-Sätze:	36/37-37/39-26-36
WGK Germany	3
RTECS-Nr.	UR2700000
TSCA	Yes
HS Code	29089990

Gefahreninformationscode (GHS)

Solvent Green 7 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
yellow to green-yellow powder
Verwenden
Pyranine is used as a fluorescent pH indicator with emission change in the physiological pH range. It acts as a dye in optical sensor applications. It finds application as a coloring agent and biological stain. It is also used in the measurement of pH of intracellular fluid in the cells.
synthetische
commonly known as Pyranine. Pyrene-1,3,6,8-tetrasulfonic acid?and 15 ~ 20% sodium hydroxide reflux, also can use ammonia water on hydrolysis reaction, this condition the product contains APTS(8-Aminopyrene-1,3,6-trisulfonic acid?).
Definition
ChEBI: Pyranine is an organic sodium salt. It has a role as a fluorochrome. It contains a pyranine(3-). It derives from a hydride of a pyrene.
Flammability and Explosibility
Not classified
Biologische Aktivität
Pyranine (HPTS; Solvent Green 7) is a pH-sensitive fluorescent indicator. Pyranine is a class of fluorescent chemosensors for Cu+ ions (λex=450 nm, λem=510 nm).
in vitro
Pyranine is capable of discriminating ranges of cations from the Cu + ion, even in competing environment. Pyranine displays a rapid fluorescence response (t 1/2 =1.66 min) towards the Cu + ion, and the micromolar detection limit enables the detection of the ion in environmental samples. The observed stoichiometry of complexation between Pyranine and Cu + is 2:1.The pH-sensitive fluorescent indicator Pyranine is studied to determine its usefulness as probes for the living cornea and anterior chamber. Adequate concentrations are reached in the cornea and anterior chamber after topical administration; measurements can be made by fluorophotometry for many hours. The pH is calculated by measuring the ratio of fluorescent intensity at two excitation wavelengths, I463/I404, a measurement which is dependent on pH but independent of the concentration of the fluorophore and other variables which can alter the intensity. In the rabbit eye, Pyranine in the cornea and anterior chamber is observed to undergo easily measurable changes in fluorescent ratios associated with lid closure and contact lens wear, indicating its sensitivity to mild changes in pH.

Properties and Applications

yellow green. Slightly soluble in glacial acetic acid, 30% hydrochloric acid, insoluble in acetic acid and 10% hydrochloric acid. Mainly used in medicine and cosmetics coloring.

Standard	Light Fastness	Heat-resistant(℃)		water	Sodium Carbonate(5%)	Hydrochloric acid(5%)
		Melting point	Stable
ISO				Dissole

läuterung methode
Purify the salt by chromatography with an alumina column, and elute with n-propanol/water (3:1, v/v). Recrystallise it from aqueous acetone (5:95, v/v) using decolorising charcoal. [Beilstein 1 III 565.] IRRITANT.

Solvent Green 7 Upstream-Materialien And Downstream Produkte

Solvent Green 7 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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