5-Chlorvalerylchlorid

Bezeichnung:5-Chlorvalerylchlorid

CAS-Nr1575-61-7

Englisch Name:5-Chlorovaleryl chloride

CBNumberCB9348033

SummenformelC5H8Cl2O

Molgewicht155.02

MOL-Datei1575-61-7.mol

Synonyma

5-Chlorvalerylchlorid

5-Chlorvalerylchlorid physikalisch-chemischer Eigenschaften

Siedepunkt	38-39 °C0.15 mm Hg(lit.)
Dichte	1.206 g/mL at 20 °C
Brechungsindex	n20/D 1.464(lit.)
Flammpunkt	195 °F
storage temp.	Store below +30°C.
Löslichkeit	Acetonitrile (Slightly), Chloroform (Sparingly)
Aggregatzustand	Liquid
Farbe	Clear colorless to slightly yellow
Wichte	1.200
PH	<7 (H2O, 20℃)
Explosionsgrenze	2.0-10.2%(V)
Wasserlöslichkeit	reacts
Sensitive	Moisture Sensitive
BRN	1745182
Stabilität	Corrosive, Moisture Sensitive
InChIKey	SVNNWKWHLOJLOK-UHFFFAOYSA-N
CAS Datenbank	1575-61-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	C,T
R-Sätze:	22-34-23-23/34
S-Sätze:	26-36/37/39-45
RIDADR	UN 3265 8/PG 2
WGK Germany	1
RTECS-Nr.	YV9108000
F	10-19-21
HazardClass	8
PackingGroup	III
HS Code	29159000

Gefahreninformationscode (GHS)

5-Chlorovaleryl chloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R34:Verursacht Verätzungen.
R23:Giftig beim Einatmen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
clear colourless to slightly yellow liquid
Verwenden
5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Application
5-Chlorovaleryl chloride is an important medicine and pesticide intermediate. It is pharmaceutically mainly for the manufacture of the medicine Cilostazole (Cilostazol) for anti-platelet aggregation, protection of vascular endothelial cells, and atherosclerosis.5-Chlorovaleryl Chloride is also for the production of paddy rice New-type wide-spectrum weedicide pyraclonil (Pyraclonil).
Allgemeine Beschreibung
5-Chlorovaleroyl chloride is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Flammability and Explosibility
Not classified
Synthese
In the existing process, producing 5-Chlorovaleryl chloride using 1,4-dichlorobutane as raw material requires a three-step reaction. First, 1,4-dichlorobutane and sodium cyanide solution are combined to form 5-chlorovaleronitrile. Then, the prepared 5-chlorovaleronitrile is hydrolyzed in concentrated hydrochloric acid to form 5-chlorovaleric acid. Finally, 5-chlorovaleronitrile reacts with thionyl chloride to generate 5-chlorovaleryl chloride.

5-Chlorovaleryl chloride Upstream-Materialien And Downstream Produkte

5-Chlorvalerylchlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1575-61-7, 5-Chlorovaleryl chloride Verwandte Suche:

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