m-PEG7-aldehyde

m-PEG7-aldehyde Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  m-PEG7-aldehyde is a PEG reagent containing an aldehyde group. Aldehyde can react with hydrazide and aminooxy groups for labeling and crosslinking carbonyls.

• Biologische Aktivität

  M-PEG7-aldehyde is a non-cleavable ADC linker for antibody drug conjugate (ADC) synthesis,it is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.

• in vitro

  ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• target

  Non-cleavable < span>

  PEGs

m-PEG7-aldehyde Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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