Anti-Transcription factor a, mitochondrial

Anti-Transcription factor a, mitochondrial Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Rabbit Anti-TFAM (AB1) antibody can be used for western blotting applications at 0.25μg/ml.

• Allgemeine Beschreibung

  Mitochondrial transcription factor A (TFAM) belongs to the high mobility group proteins and is required for mitochondrial DNA (mtDNA) maintenance. Studies have reported that human mtDNA is packed with TFAM.
  Rabbit Anti-TFAM (AB1) antibody recognizes bovine, canine, human, mouse, and pig TFAM.

• Biochem/physiol Actions

  TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.

Anti-Transcription factor a, mitochondrial Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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