DRF-1042

DRF-1042 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  DRF-1042 is an orally active camptothecin analog that inhibits DNA topoisomerase I (DNA topoisomerase I). DRF-1042 shows promising anticancer activity against a panel of human cancer cell lines, including multidrug resistant (MDR) phenotypes.

• in vitro

  DRF-1042 demonstrates superior lactone stability and good in vitro anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype.

• in vivo

  In clonogenic assay against murine, canine and human bone marrow cells, DRF-1042 treatment shows less mylosupression that supports the possibility of protracted dose schedule in both experimental and clinical studies.

• target

  DNA topoisomerase I

DRF-1042 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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