Cholsure

Bezeichnung:Cholsure

CAS-Nr81-25-4

Englisch Name:Cholic acid

CBNumberCB9263222

SummenformelC24H40O5

Molgewicht408.57

MOL-Datei81-25-4.mol

Synonyma

Cholsure

Cholsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	200-201 °C (lit.)
Siedepunkt	449.08°C (rough estimate)
alpha	36 º (c=0.6, 95% EtOH)
Dichte	1.0310 (rough estimate)
Brechungsindex	1.5800 (estimate)
Flammpunkt	9℃
storage temp.	2-8°C
Löslichkeit	methanol: 0.1 g/mL, clear
pka	4.98(at 20℃)
Aggregatzustand	Solid
Farbe	White to Brown
Wasserlöslichkeit	0.28 g/L (15 ºC)
Merck	14,2203
BRN	2822009
InChIKey	BHQCQFFYRZLCQQ-OELDTZBJSA-N
LogP	2.03-2.615 at 20℃
CAS Datenbank	81-25-4(CAS DataBase Reference)
NIST chemische Informationen	Cholic acid(81-25-4)
EPA chemische Informationen	Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- (81-25-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	24/25-36-26
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	2
RTECS-Nr.	FZ9350000
TSCA	Yes
HS Code	29181990
Giftige Stoffe Daten	81-25-4(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Cholic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to light beige crystalline powder
Verwenden
asthma therapeutic
Verwenden
Choleretic produced by, and isolated from liver cells.
Verwenden
Cholic Acid is an emulsifier that exists as colorless plates or a white crystalline powder which has a bitter taste with a sweetish aftertaste. it is slightly soluble in water. it functions as an emulsifying agent in egg white.
Definition
ChEBI: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Allgemeine Beschreibung
This Certified Spiking Solution^? is suitable as a starting material in preparation of linearity standards, calibrators, and controls for use in LC-MS/MS and GC/MS bile acid testing methods. Cholic acid is a primary bile acid that plays an important role in cholesterol homeostasis and intestinal absorption of dietary vitamins and lipids. Levels of cholic acid can serve as markers for inborn and acquired hepatobiliary disorders such as biliary atresia and familial intrahepatic cholestasis as well as inborn errors of bile acid synthesis and sclerosing cholangitis.
Flammability and Explosibility
Non flammable
läuterung methode
This bile acid crystallises from H2O or wet Et2O (as hydrate) or EtOH (as alcoholate). Dry it under vacuum at 94o. When an alcoholic solution of cholic acid + I2 is added to aqueous KI, it forms a molecular compound (C24H40O5I)4 KI. H2O. The methyl ester is dimorphic with m 155o and 162o and [] D 20 +25o (EtOH). [Anderson et al. Biochem J 67 323 1957, 85 236 1962, Beilstein 10 III 2162, IV 2071.]

Cholic acid Upstream-Materialien And Downstream Produkte

Cholsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

81-25-4, Cholic acid Verwandte Suche:

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