Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline

Decahydro-1-methyl-5,7-diphenyl-6-(3,4,5,6-tetrahydropyridin-2-yl)quinoline Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  This alkaloid was first isolated by Manske from Lobelia cardinalis L. It crystallizes with difficulty from EtOH yielding colourless prisms and has [o:l54 + 22.3° (CHCI 3). The hydrochloride sesquihydrate has m.p. 220°C. Oxidation of the alkaloid with KMn04 yields benzoic acid. Pharmacologically, the alkaloid shows few, if any, of the typical characteristics of lobeline (q.v.).

• Einzelnachweise

  Manske., Can. 1. Res., 16B, 445 (1938)
  Pharmacology:
  See pharmacological note made by Unna in the above reference.
  Biosynthesis:
  Gupta, Spenser., Chern. Commull., 893 (1966)