2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC₅₀ = 0.8 μg/ml). It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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