N-Isopropylbenzylamin

Bezeichnung:N-Isopropylbenzylamin

CAS-Nr102-97-6

Englisch Name:N-Isopropylbenzylamine

CBNumberCB9199936

SummenformelC10H15N

Molgewicht149.23

MOL-Datei102-97-6.mol

Synonyma

N-Isopropylbenzylamin

N-Isopropylbenzylamin physikalisch-chemischer Eigenschaften

Schmelzpunkt	143°C (estimate)
Siedepunkt	200 °C(lit.)
Dichte	0.892 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.502(lit.)
Flammpunkt	190 °F
storage temp.	Store below +30°C.
Löslichkeit	Chloroform (Slightly), Ethy Acetate (Slightly), Methanol (Slightly)
Aggregatzustand	Oil
pka	9.77±0.19(Predicted)
Farbe	Colourless
BRN	2638437
InChIKey	LYBKPDDZTNUNNM-UHFFFAOYSA-N
CAS Datenbank	102-97-6(CAS DataBase Reference)
NIST chemische Informationen	Benzenemethanamine, N-(1-methylethyl)-(102-97-6)
EPA chemische Informationen	Benzenemethanamine, N-(1-methylethyl)- (102-97-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
RIDADR	2735
WGK Germany	3
TSCA	Yes
HazardClass	8
PackingGroup	III
HS Code	29214980

Gefahreninformationscode (GHS)

N-Isopropylbenzylamine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
CLEAR VERY SLIGHTLY YELLOW TO YELLOW LIQUID
Verwenden
N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA.
Application
N-Isopropylbenzylamine was used as ligand in the preparation and characterization of bis(cyclopentadienyl)magnesium. It was also used in the synthesis of N-benzylideneisopropylamine-N-oxide.
synthetische
N-benzylisopropylamine is synthesized by the reduction reaction of N-isopropylbenzamide or prepared from benzylamine and acetone by reductive amination reaction.
Allgemeine Beschreibung
N-isopropylbenzylamine is a structural isomer of methamphetamine, is one of the most common adulterants. It forms amine adducts with magnesocene at ambient temperature in toluene.
Cytotoxicity
The toxicity of N-isopropylbenzylamine was evaluated in SH-SY5Y, PC12, and SN4741 cell lines. Cells were treated with 0.3–10 mM N-isopropylbenzylamine for 24 hours, and cell viability was measured using MTT assay. N-isopropylbenzylamine concentration-dependently reduced cell viability in these cells. The IC50 values of N-isopropylbenzylamine on cell viability were 3.47, 1.49, and 3.21 mM for SH-SY5Y cells, PC12 cells, and SN4741 cells, respectively. N-isopropylbenzylamine produced toxicity in cell lines that model neurons. Moreover, the activation of nNOS and the production of intracellular NO might be involved in N-isopropylbenzylamine-induced toxicity in SN4741 cells[1].
Einzelnachweise
[1] Peng Xu . “N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro.” Toxicology 480 (2022): Article 153337.

N-Isopropylbenzylamine Upstream-Materialien And Downstream Produkte

N-Isopropylbenzylamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

102-97-6, N-Isopropylbenzylamine Verwandte Suche:

Send Inquriy