15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER

15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  15(R)-15-methyl Prostaglandin F_2α methyl ester (15(R)-15-methyl PGF_2α methyl ester) is a lipid soluble prodrug form of 15(R)-15-methyl PGF_2α with increased membrane permeability. Acid-catalyzed epimerization of 15(R)-15-methyl PGF_2α methyl ester and hydrolysis of the ester converts it into the active 15(S)-15-methyl PGF_2α .^1,2

• Einzelnachweise

  1. Plaisted, S.M., DeZwaan, J., and Snider, B.G. High-performance liquid chromatographic determination of acid-catalyzed degradation products of methyl carboprost in a polymeric controlled-release device J. Chromatogr. 314,369-377(1984).
  2. Hamberg, M., Zhang, L.Y., and Bergstr?m, S. On the pH-dependent degradation of 15(S)-15 methyl-prostaglandin F_2α (Carboprost) Eur. J. Pharm. Sci. 3(1),27-38(1995).

15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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