RUPATADINE

RUPATADINE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Clinical Use

  Antihistamine

• Arzneimittelwechselwirkung

  Potentially hazardous interactions with other drugs
  Antibacterials: concentration increased by clarithromycin and erythromycin - use with caution.
  Antifungals: concentration increased by itraconazole, ketoconazole, posaconazole and voriconazole - avoid; use fluconazole with caution.
  Antivirals: concentration possibly increased by ritonavir and other protease inhibitors - avoid.
  Grapefruit juice: concentration increased - avoid.
  Lipid-lowering agents: use in combination with statins with caution.
  Ciclosporin, sirolimus, tacrolimus - concentration possibly increased by rupatadine.

• Stoffwechsel

  Mainly metabolised by the cytochrome P450 (CYP 3A4) enzyme pathway. The amounts of unaltered active substance found in urine and faeces were insignificant. This means that rupatadine is almost completely metabolised.

RUPATADINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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