2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaen

Bezeichnung:2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaen

CAS-Nr111-02-4

Englisch Name:Squalene

CBNumberCB8855316

SummenformelC30H50

Molgewicht410.72

MOL-Datei111-02-4.mol

Synonyma

2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaen

2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaen physikalisch-chemischer Eigenschaften

Schmelzpunkt	−75 °C(lit.)
Siedepunkt	285 °C25 mm Hg(lit.)
Dichte	0.858 g/mL at 25 °C(lit.)
Dampfdruck	0Pa at 25℃
Brechungsindex	n20/D 1.494(lit.)
Flammpunkt	>230 °F
storage temp.	2-8°C
Löslichkeit	DMSO : 16.67 mg/mL (40.59 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
Aggregatzustand	liquid
Farbe	light yellow
Geruch (Odor)	oil, faint odor
Wasserlöslichkeit	<0.1 g/100 mL at 19 ºC
Merck	14,8768
BRN	1728919
LogP	14.12 at 24℃
CAS Datenbank	111-02-4(CAS DataBase Reference)
NIST chemische Informationen	2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (all-E)-(111-02-4)
EPA chemische Informationen	Squalene (111-02-4)

Sicherheit

S-Sätze:	24/25
WGK Germany	2
RTECS-Nr.	XB6010000
F	8-10-23
TSCA	Yes
HS Code	29012980
Giftige Stoffe Daten	111-02-4(Hazardous Substances Data)
Toxizität	mouse,LD50,intravenous,1800mg/kg (1800mg/kg),Japanese Journal of Cancer Research. Vol. 76, Pg. 1021, 1985.

Gefahreninformationscode (GHS)

Squalene Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
clear colourless to faint yellow oil
Verwenden
cosmetic and pharmaceutical excipient
Verwenden
Squalene is a natural triterpene that plays an important role in the synthesis of cholesterol, steroid hormones, and vitamin D in the human body. Squalene is commonly used as a biochemical precursor i n the preparation of steroids. Squalene is also a natural moisturizer with low acute toxicity and is not significant human skin irritants or sensitizers.
Verwenden
Bactericide; intermediate in manufacture of pharmaceuticals, organic coloring materials, rubber chemicals, aromatics and surface active agents.
Vorbereitung Methode
Squalene is extracted from shark liver or synthesized from hexaphenyl-1,4-butanediyldiphosphonium dibromide and 6,10-dimethyl-5,9-undecadien-2-one (geranylacetone, industrial intermediate in the vitamin E synthesis).
Definition
ChEBI: A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration.
Allgemeine Beschreibung
Clear, slightly yellow liquid with a faint odor. Density 0.858 g / cm3.
Air & Water Reaktionen
May become discolored on exposure to air. Insoluble in water.
Reaktivität anzeigen
(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene is incompatible with strong oxidizing agents. .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition (all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene emits toxic fumes of carbon monoxide and carbon dioxide.
Brandgefahr
(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene is probably combustible.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
Squalene is a biosynthetic precursor to all steroids. It acts as a cytoprotective agent to normal cells exposed to carcinogens and antitumor agents. Squalene helps in equalizing the blood cholesterol levels. It increases the production of HDL (high density lipoprotein) and the excretion of LDL (low density lipoprotein). This helps in reducing the risk of heart disease and protects the less stable body fats from oxidation. It is also used in treating hypercholesterolemia. Squalene is known to improve the efficiency of cholesterol lowering drugs. It also serves as an antioxidant by preventing the effects of free radical. It protects skin from drying and other environmental conditions such as oxidation, ultraviolet rays and pollutants. Squalene is known to promote wound healing.
target
COX | STAT | FOXP3 | Nrf2 | SOD | GPx

Squalene Upstream-Materialien And Downstream Produkte

2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

111-02-4, Squalene Verwandte Suche:

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