Triphenylessigsure

Bezeichnung:Triphenylessigsure

CAS-Nr595-91-5

Englisch Name:Triphenylacetic acid

CBNumberCB8675374

SummenformelC20H16O2

Molgewicht288.35

MOL-Datei595-91-5.mol

Synonyma

Triphenylessigsure

Triphenylessigsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	270-273 °C (lit.)
Siedepunkt	390.57°C (rough estimate)
Dichte	1.0992 (rough estimate)
Brechungsindex	1.7580 (estimate)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Fine Crystalline Powder
pka	pK1:3.96 (25°C)
Farbe	White to beige
InChI	InChI=1S/C20H16O2/c21-19(22)20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H,(H,21,22)
InChIKey	DCYGAPKNVCQNOE-UHFFFAOYSA-N
SMILES	C(C1C=CC=CC=1)(C1C=CC=CC=1)(C1C=CC=CC=1)C(=O)O
CAS Datenbank	595-91-5(CAS DataBase Reference)
NIST chemische Informationen	Triphenylacetic acid(595-91-5)

Sicherheit

Kennzeichnung gefährlicher	Xi
S-Sätze:	24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29163900

Gefahreninformationscode (GHS)

Triphenylacetic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to beige fine crystalline powder
Verwenden
2,2,2-Triphenylacetic Acid is used in preparation of Rhodium(II) Tetramethyl-benzenedipropioate complex, other Carboxylate complexes, and their catalytic activity.
Application
Triphenylacetic acid could be used to seal dye molecules within MOF-5. Introducing triphenylacetic acid (TPAA) capping groups traps organic dyes such as crystal violet (CV) within the MOF crystals. Surface-bound TPAA groups block the MOF pores, preventing the encapsulated dye from diffusing into the solution. Liberating the TPAA from the surface by protonation can reverse guest trapping, but acidic conditions can also degrade the MOF by extruding the carboxylate struts. In addition, triphenylacetic acid could inhibit microsomal bilirubin UDPglucuronosyltransferase activity in rat liver. This compound competitively inhibits bilirubin UDP-glucuronosyltransferase with respect to bilirubin[2-3].
Synthesis Reference(s)
The Journal of Organic Chemistry, 28, p. 1725, 1963 DOI: 10.1021/jo01041a520
Reaktivität anzeigen
Triphenylacetic acid can be selectively fluorinated in dimethylsulfoxide/ HgF2 solutions under UV-visible illumination[1].
Einzelnachweise
[1] Habibi, Mohammed H., and T. E. Mallouk. "Photochemical selective fluorination of organic molecules using mercury (II) fluoride." Journal of Fluorine Chemistry 51.2(1991):291-294.
[2] Yan, J. , et al. "On-demand guest release from MOF-5 sealed with nitrophenylacetic acid photocapping groups. " Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 18.12(2019):2849-2853.
[3] Fournel, S, et al. "Inhibition of bilirubin UDPglucuronosyltransferase activity by triphenylacetic acid and related compounds. " BBA - General Subjects 883.2(1986):190-196.

Triphenylacetic acid Upstream-Materialien And Downstream Produkte

Triphenylessigsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

595-91-5, Triphenylacetic acid Verwandte Suche:

Send Inquriy