(E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol

Bezeichnung:(E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol

CAS-Nr40716-66-3

Englisch Name:Nerolidol

CBNumberCB8497598

SummenformelC15H26O

Molgewicht222.37

MOL-Datei40716-66-3.mol

Synonyma

(E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol

(E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol physikalisch-chemischer Eigenschaften

Siedepunkt	145-146 °C12 mm Hg(lit.)
Dichte	0.876 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.479(lit.)
Flammpunkt	230 °F
storage temp.	-20°C
Löslichkeit	DMF: miscible,DMSO: miscible,Ethanol: miscible,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
Aggregatzustand	Liquid
pka	14.40±0.29(Predicted)
Farbe	Colorless to light yellow
Geruch (Odor)	at 100.00 %. floral green citrus woody waxy
Geruchsart	floral
JECFA Number	1646
Merck	13,6501
BRN	5731231
Stabilität	Light Sensitive
LogP	5.316 (est)
NIST chemische Informationen	1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (e)-(40716-66-3)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
F	10-23
Toxizität	Both the acute oral LD₅₀ in rats and the acute dermal LD₅₀ in rabbits exceeded 5 g/kg (Russell. 1973).

Gefahreninformationscode (GHS)

Nerolidol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
trans-Nerolidol is a sesquiterpene that has been found in various plants, including C. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties. In a disc assay, trans-nerolidol inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae with zones of inhibition measuring 10, 9, 10, and 4 mm, respectively. It reduces viability of CaCo-2 adenocarcinoma cells with an IC₅₀ value of 28.7 mg/L and reduces production of reactive oxygen species (ROS). trans-Nerolidol is insecticidal against A. aegypti larvae with a 24-hour LC₅₀ value of 9 mg/L.
Occurrence
Reported to be found in cabreuva oil, oil of neroli, balsam Peru, ylang ylang and many others (Gildemeister & Hoffman, 1959).
Verwenden
Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.
synthetische
By isolation from a suitable essential oil or by chemical synthesis.
Definition
ChEBI: Nerolidol is a farnesane sesquiterpenoid that is dodeca-1,6,10-triene which carries methyl groups at positions 3, 7 and 11 and a hydroxy group at position 3. It is a natural product that is present in various flowers and plants with a floral odor. Chemically, it exists in two geometric isomers, trans and cis forms. It is widely used in cosmetics (e.g. shampoos and perfumes), in non-cosmetic products (e.g. detergents and cleansers) and also as a food flavoring agent. It has a role as a flavouring agent, a cosmetic, a pheromone, a neuroprotective agent, an antifungal agent, an anti-inflammatory agent, an antihypertensive agent, an antioxidant, a volatile oil component, an insect attractant and a herbicide. It is a farnesane sesquiterpenoid, a tertiary allylic alcohol and a volatile organic compound.

Nerolidol Upstream-Materialien And Downstream Produkte

(E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

40716-66-3, Nerolidol Verwandte Suche:

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