eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem

eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

• Allgemeine Beschreibung

  A cell-permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Shown to offer protection against ER stress-induced apoptosis (EC₅₀ ~15 μM in PC12 cells stimulated with 750 ng/ml of Tunicamycin (Cat. No. 654380). Prevents HSV replication both in Vero cells (IC₅₀ ~3 μM for reducing plaque formation) in vitro and in a mouse cornea infection model in vivo. The solid form of this compound (Cat. No. 324895) is also available.

• Biochem/physiol Actions

  Cell permeable: yes

eIF-2α Inhibitor, Salubrinal - CAS 304475-63-6 - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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