Methylpyruvat

Bezeichnung:Methylpyruvat

CAS-Nr600-22-6

Englisch Name:Methyl pyruvate

CBNumberCB8405108

SummenformelC4H6O3

Molgewicht102.09

MOL-Datei600-22-6.mol

Synonyma

Methylpyruvat

Methylpyruvat physikalisch-chemischer Eigenschaften

Schmelzpunkt	-22 °C
Siedepunkt	134-137 °C (lit.)
Dichte	1.13 g/mL at 25 °C (lit.)
Brechungsindex	n20/D 1.404(lit.)
Flammpunkt	103 °F
storage temp.	2-8°C
Löslichkeit	ethanol: soluble1.1g/10 mL, clear, colorless to almost colorless
Aggregatzustand	liquid
Farbe	Yellow
Wasserlöslichkeit	Soluble in chloroform, methanol, ether, alcohol. Slightly soluble in water.
Merck	14,8021
BRN	1361953
LogP	-0.159 (est)
CAS Datenbank	600-22-6(CAS DataBase Reference)
NIST chemische Informationen	Propanoic acid, 2-oxo-, methyl ester(600-22-6)

Sicherheit

Kennzeichnung gefährlicher	Xi,F
R-Sätze:	10
S-Sätze:	23-24/25-16
RIDADR	UN 3272 3/PG 3
WGK Germany	3
F	10-21
HazardClass	3
PackingGroup	III
HS Code	29183000

Gefahreninformationscode (GHS)

Methyl pyruvate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R10:Entzündlich.
S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Methyl pyruvate is a clear, light yellow, and flammable liquid.
Verwenden
Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increases free calcium ion concentration in the cytosol of pancreatic cells. It is used in the preparation of dimethyl 2,3-dimethylenebutanedioate.
Verwenden
Methyl pyruvate may be used to investigate the adsorption and reactivity of methyl pyruvate on Pt{111}. It may be used in the preparation of dimethyl 2,3-dimethylenebutanedioate.
synthetische
Methyl pyruvate has been prepared from the silver salt of pyruvic acid and methyl iodide; from the free acid, by the ethanol-vapor method without a catalyst, by azeotropic removal of the water produced by the reaction of methanol in the presence of p-toluenesulfonic acid (the present method), and by refluxing with methanol in ethylene dichloride using ethanesulfonic acid as a catalyst (73% yield). Pyruvic esters have also been prepared by the catalytic dehydrogenation of lactic acid esters and by the oxidation of ethyl lactate with potassium permanganate.
DOI: 10.15227/orgsyn.024.0072
Definition
ChEBI: Methyl pyruvate is a pyruvate ester resultinf grom the formal condensation of the carboxy group of pyruvic acid with the hydroxy group of methanol. It is a pyruvate ester and a methyl ester. It derives from a pyruvic acid.
Allgemeine Beschreibung
Methyl pyruvate is a pyruvic ester. Surface conditions during Pt/silica EUROPT-1 modified by cinchonidine catalyzed by enantioselective hydrogenation of methyl pyruvate to R-(+)-methyl lactate were investigated. Enantioselective hydrogenation of methyl pyruvate over finely dispersed polyvinylpyrrolidone-stabilized and the corresponding alumina-supported iridium clusters modified with cinchonidine was studied. The molecular orientation and conformation of methyl pyruvate on Ni(111) surface has been investigated in the temperature range 105-220K. Methyl pyruvate is reported to stimulate insulin secretion in vitro and in vivo.

Methyl pyruvate Upstream-Materialien And Downstream Produkte

Methylpyruvat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

600-22-6, Methyl pyruvate Verwandte Suche:

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