Isobutyramid

Bezeichnung:Isobutyramid

CAS-Nr563-83-7

Englisch Name:Isobutyramide

CBNumberCB8344674

SummenformelC4H9NO

Molgewicht87.12

MOL-Datei563-83-7.mol

Synonyma

Isobutyramid

Isobutyramid physikalisch-chemischer Eigenschaften

Schmelzpunkt	127-131 °C (lit.)
Siedepunkt	216-220 °C (lit.)
Dichte	1.013 g/mL at 25 °C (lit.)
Brechungsindex	1.4345 (estimate)
Flammpunkt	216-220°C
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Chloroform (Sparingly), DMSO (Slightly)
Aggregatzustand	Solid
pka	16.60±0.50(Predicted)
Farbe	White to Off-White
Wasserlöslichkeit	Soluble in water.
LogP	0.003 (est)
CAS Datenbank	563-83-7(CAS DataBase Reference)
NIST chemische Informationen	Propanamide, 2-methyl-(563-83-7)
EPA chemische Informationen	Propanamide, 2-methyl- (563-83-7)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
S-Sätze:	24/25
WGK Germany	3
RTECS-Nr.	TX1475000
TSCA	Yes
HS Code	29241990

Gefahreninformationscode (GHS)

Isobutyramide Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white needle-like crystalline powder
Verwenden
Isobutyramide could be a useful compound for technical applications as a component in environmentally-friendly automobile welding anti-spatter liquid.
Verwenden
Isobutyramide plays an important role in chemical grafting of human serum albumin during the synthesis of sequentially assembled protein capsules. It is used in pharmaceutical manufacturing and in cellular differentiation. It finds application in the transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. Further, it is in the treatment of beta-thalassemia and sickle cell disease.
Application
Isobutyramide was used for chemical grafting of human serum albumin during the synthesis of sequentialy assembled protein capsules.
Isobutyramide plays an important role in chemical grafting of human serum albumin during the synthesis of sequentially assembled protein capsules. It is used in pharmaceutical manufacturing and in cellular differentiation. It finds application in the transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. Further, it is in the treatment of beta-thalassemia and sickle cell disease.
Definition
ChEBI: Isobutyramide is a carboximidic acid.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 2058, 1947 DOI: 10.1021/ja01200a070
Biochem/physiol Actions
Isobutyramide activates transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. It is useful in the treatment of β-thalassemia and sickle cell disease.
läuterung methode
Crystallise the amide from acetone, *benzene, CHCl3, EtOAc or water, then dry it under vacuum over P2O5 or 99% at H2SO4, or at 70o/3hours in a desiccator. Sublime it under vacuum. [Kent & McAlvain Org Synth Coll Vol III 491 1955, Beilstein 2 H 293, 2 I 129, 2 II 262, 2 III 654, 2 IV 852.]

Isobutyramide Upstream-Materialien And Downstream Produkte

Isobutyramid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

563-83-7, Isobutyramide Verwandte Suche:

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