2-(Dicyclohexylphosphino)biphenyl

Bezeichnung:2-(Dicyclohexylphosphino)biphenyl

CAS-Nr247940-06-3

Englisch Name:2-(Dicyclohexylphosphino)biphenyl

CBNumberCB8325019

SummenformelC24H31P

Molgewicht350.48

MOL-Datei247940-06-3.mol

2-(Dicyclohexylphosphino)biphenyl physikalisch-chemischer Eigenschaften

Schmelzpunkt	102-106 °C(lit.)
Siedepunkt	499.5±24.0 °C(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
Löslichkeit	soluble in Toluene
Aggregatzustand	crystal
Farbe	white
Sensitive	Air Sensitive
BRN	8440533
InChI	InChI=1S/C24H31P/c1-4-12-20(13-5-1)23-18-10-11-19-24(23)25(21-14-6-2-7-15-21)22-16-8-3-9-17-22/h1,4-5,10-13,18-19,21-22H,2-3,6-9,14-17H2
InChIKey	LCSNDSFWVKMJCT-UHFFFAOYSA-N
SMILES	P(C1=CC=CC=C1C1=CC=CC=C1)(C1CCCCC1)C1CCCCC1
CAS Datenbank	247940-06-3(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	36/37/38-22
S-Sätze:	36/37/39-26
WGK Germany	3
F	10-13-23
TSCA	No
HazardClass	AIR SENSITIVE
HS Code	29310099

Gefahreninformationscode (GHS)

2-(Dicyclohexylphosphino)biphenyl Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
2-(Dicyclohexylphosphino)biphenyl is a ligand for the amination of triflates and aryl halides. Optimal ligand for a novel amination reaction (Buchwald reaction)(2) 2-(Dicyclohexylphosphino)biphenyl, a synthetic chemical compound, has found diverse applications in scientific research. Being a cyclic phosphonate derivative of cyclohexanol, this colourless, odourless, and tasteless solid holds a distinct appeal for laboratory use. In scientific research, 2-(Dicyclohexylphosphino)biphenyl has proven invaluable. It serves as an excellent model compound for delving into protein-ligand interactions, thus aiding in studying small molecule effects on protein folding. Moreover, researchers have utilized 2-(Dicyclohexylphosphino)biphenyl to gain insights into protein structures and unravel the mechanism of action behind various drugs. Additionally, the compound has been a vital tool in assessing how environmental factors influence protein structure and function. The interaction between 2-(Dicyclohexylphosphino)biphenyl and proteins primarily occurs through hydrogen bonding and hydrophobic interactions, resulting in high-affinity and specific protein binding.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
suzuki reaction
Verwenden
Ligand employed in an extremely general method for the Pd-catalyzed synthesis of aromaticamines using aryl chlorides, bromides and triflates.
Verwenden
2-(Dicyclohexylphosphino)biphenyl is used as a catalyst for Suzuki coupling reactions.
Allgemeine Beschreibung
CyJohnPhos [(2-Biphenyl)dicyclohexylphosphine] is an air-stable, bulky and electron-rich monodentate biarylphosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

2-(Dicyclohexylphosphino)biphenyl Upstream-Materialien And Downstream Produkte

2-(Dicyclohexylphosphino)biphenyl Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

247940-06-3, 2-(Dicyclohexylphosphino)biphenyl Verwandte Suche:

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