Fexofenadine-d10 Hydrochloride

Fexofenadine-d10 Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Fexofenadine-d₁₀ is intended for use as an internal standard for the quantification of fexofenadine by GC- or LC-MS. Fexofenadine is a histamine H₁ receptor antagonist (K_i = 10 nM). It reverses contraction of isolated rat tracheal strips induced by acetyl-β-methylcholine . Fexofenadine inhibits expression of IL-8 in TNF-α-stimulated HCT116 and COLO 205 cells. Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-IκB kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; ).

• Verwenden

  Fexofenadine-d10 Hydrochloride is the labeled analogue of Fexofenadine Hydrochloride (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.

Fexofenadine-d10 Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(15)Suppliers