Diazoacetylbenzene

Diazoacetylbenzene Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  α-Diazoacetophenone is used as a precursor to carbenes and carbenoids; reagent for preparation of sulfonium, oxonium, and pyridinium ylides; 1,3 dipole for heterocycle synthesis; reagent for Lewis acid or transition metal-mediated insertion reactions; reagent for cyclopropanation of alkenes and for aromatic annulation.

• synthetische

  Preparative Methods of α-Diazoacetophenone: an improved method of synthesis of diazo ketones has been recently published, via acylation of the lithium enolate of the ketone with 2,2,2-Trifluoroethyl Trifluoroacetate and subsequent reaction with Methanesulfonyl Azide. ^[1] Alternatively, acylation of diazomethane with aroyl chlorides in the presence of triethylamine provides a general method for the synthesis of aromatic diazo ketones.^[2]

• Lager

  diazoacetophenone is a skin irritant; therefore direct contact should be avoided. Diazoacetophenone has shown microbial mutagenicity.

• Einzelnachweise

  1. Danheiser, R. L.; Miller, R. F.; Brisbois, R. G.; Park, S. Z. JOC 1990, 55, 1959.
  2. Bridson, J. N.; Hooz, J. OS 1973, 53, 35.

Diazoacetylbenzene Upstream-Materialien And Downstream Produkte

Diazoacetylbenzene Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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