Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat

Bezeichnung:Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat

CAS-Nr860-22-0

Englisch Name:Indigo Carmine

CBNumberCB8231484

SummenformelC16H11N2NaO8S2

Molgewicht446.38

MOL-Datei860-22-0.mol

Synonyma

Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat

Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat physikalisch-chemischer Eigenschaften

Schmelzpunkt	>300°C
chüttdichte	700-900kg/m3
Dichte	1.01 g/mL at 20 °C
Brechungsindex	n20/D 1.335
storage temp.	room temp
Löslichkeit	1g/l
Colour Index	73015
Aggregatzustand	Powder/Solid
Farbe	Very dark blue to purple
Geruch (Odor)	Light odour
PH	7 (10g/l, H2O, 20℃)
Säure-Base-Indikators(pH-Indikatoren)	11.5(blue)-14.0(yellow)
Wasserlöslichkeit	1 g/100 mL (25 ºC)
maximale Wellenlänge (λmax)	608nm
Sensitive	Light Sensitive
Merck	14,4944
BRN	4103904
Stabilität	Stable. Incompatible with strong oxidizing agents.
Biologische Anwendungen	Detecting microorganisms; treating amyloidosis,testicular cancer; medical devices; drug delivery system
Major Application	Display device, sensor, chemical-mechanical polishing, batteries, photographic materials, thermoplastics, inks, highlighters, detergents, disinfectants, rodenticide, colored bubbles, hair dyes, cosmetics, food, determine bacterial growth, antiischemic Magents, antiseptic, antitumor agents, Alzheimer’s disease, psychoactive drugs, Tooth whitening
Kosmetik-Inhaltsstoffe Funktionen	HAIR DYEING COLORANT
InChIKey	KHLVKKOJDHCJMG-QDBORUFSSA-L
SMILES	[Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
LogP	-3.57
CAS Datenbank	860-22-0(CAS DataBase Reference)
EPA chemische Informationen	C.I. Acid Blue 74 (860-22-0)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37/38
S-Sätze:	22-24/25-36/37/39-27-26
WGK Germany	3
RTECS-Nr.	DU3000000
TSCA	TSCA listed
HS Code	32041200
Speicherklasse	11 - Combustible Solids
Hazard Classifications	Skin Sens. 1
Giftige Stoffe Daten	860-22-0(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: > 2000 mg/kg

Gefahreninformationscode (GHS)

Indigo Carmine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Indigo carmine is indigotindisulfonate sodium, a marker dye used during cystoscopy and ureteral catheterization.
(1) Indigo carmine is also used in endoscopic procedures, lymph node and vessel delineation, and for tumor localization. Indigo carmine is an unapproved drug without FDA approved labeling.
(2) There is no single dye that can replace indigo carmine. Choice of alternative agent will depend on type of procedure and physician discretion, as well as product availability.
Indigo Carmine (IC) is the most common chemical dye for clothes dyeing, which is considered as a refractory molecule since it is required a rather strong chemical treatment for its elimination from the water waste. The presence of this dye in residuals causes notorious change of water color and smell even in very low concentration. Moreover, if some of this water reaches natural streams it can be toxic for aquatic living entities due to the formation of toxic compounds such as aromatic amines.
Chemische Eigenschaften
FD & C Blue No. 2 is principally the disodium salt of 2-( 1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro3-oxo-lH-indole-5-sulfonic acid.
The colorant is a blue-brown to red-brown powder that dissolves in water to give a solution that is blue at neutrality, blue-violet in acid, and green to yellow-green in base. When dissolved in concentrated sulfuric acid, it yields a blue-violet solution that turns blue when diluted with water. It is soluble in 95% ethanol.
FD & C Blue No. 2 is used in dessert powders, bakery goods, cereals, snack foods, confectionery products, maraschino cherries, sausage, ice cream, sherbet, and dairy products. The color is also used in drug preparations.1 .
Chemische Eigenschaften
purple powder
Verwenden
Indigo Carmine (FD&C Blue #2) is a colorant. It has poor ph stability in that after 1 week at ph 3 and 5 it will appreciably fade, at ph 7 considerably fade, and at ph 8 fade completely. It is the least soluble of all food colors, with a solubility of 1.6 g in 100 ml of water at 25°c. Complete fading occurs in alkalis such as 10% sodium carbonate and 10% sodium hydroxide, with fading also occurring in 10% sugar systems. It has very poor light stability and oxidation stability, and moderate stability to heat; it has a deep blue hue with poor tinctorial strength. It is the only food color that has good resistance to reducing agents, but has very poor compatibility with food components. The major use is in pet food, but it is also used in candies, confections, and baked goods. The common name is indigotine.
Verwenden
5,5’Indigodisulfonic Acid Disodium Salt is a food additive that is widely used in the market. 5,5’Indigodisulfonic Acid Disodium Salt was also used as a dye for cationic cotton fabrics.
Verwenden
Colorant for nylon, surgical sutures, foods and ingested drugs. As a reagent for functional kidney tests, for detection of nitrates, chlorates and in testing milk.
synthetische
3H-indol-3-one,2-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydrowith strong sulfuric acid or trace fuming sulfuric acid products.
Definition
ChEBI: An organic sodium salt resulting from the formal condensation of indigo carmine (acid form) with two equivalents of sodium hydroxide. It is an indicator at pH 11.5-14, changing from blue to yellow.
Trademarks
Indigo Carmine (Becton Dickinson Microbiology).
Allgemeine Beschreibung
Indigo to dark blue powder.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
Sensitive to light. Very sensitive to oxidizing agents. Color is readily discharged by nitric acid, chlorates, etc. Color of aqueous solutions fades on standing.
Brandgefahr
Flash point data for Acid Blue 74 is not available, but Acid Blue 74 is probably combustible.
Biochem/physiol Actions
Indigo Carmine (IC), commonly known as acid blue 74 or food blue 1 or FD and C blue 2 is a blue synthetic dye. It is used as a redox indicator in analytical chemistry and as a microscopic stain in biology. IC is also employed as a photometric detector. IC is a highly toxic indigoid dye and is associated with various health hazards such as irritation to the gastrointestinal tract leading to nausea, vomiting, and diarrhea and irritation in the respiratory tract leading to coughing and shortness of breath. IC exposure might also cause skin and eye irritations to humans. IC dye spray is used for the diagnosis of dysplasia in ulcerative colitis and is considered to be a simple, feasible, and safe method.

Properties and Applications

green light blue. Soluble in water for blue, slightly soluble in alcohol. The strong sulfuric acid is a deep blue light in purple, diluted into blue. In aqueous solution for green to yellow sodium hydroxide to join.

Standard	Light Fastness	Soaping		Persperation Fastness	Oxygen bleaching		Fastness to seawater
Standard	Light Fastness	Fading	Stain	Persperation Fastness	Fading	Stain	Fading	Stain
ISO	1-2	2	4	2	1	2	2	1
AATCC	1	3	5	1	1	1	2	2

läuterung methode
Its solubility in H2O is 1g/100mL at 25o. It has been purified by dissolving in H2O, filtering and adding EtOH to cause the salt to separate. Wash the solid with EtOH, Et2O and dry in vacuo. [V.rlander & Schubert Chem Ber 34 1860 1901, UV: Smit et al. Anal Chem 27 1159 1955, Preisler et al. J Am Chem Soc 81 1991 1959, Beilstein 25 IV 1975.]
Einzelnachweise
American Society of Health-system Pharmacist.
Journal of Environmental Protection, 2016, 7, 1693-1706

Indigo Carmine Upstream-Materialien And Downstream Produkte

Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

860-22-0, Indigo Carmine Verwandte Suche:

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