Biphenyl-4-ol

Bezeichnung:Biphenyl-4-ol

CAS-Nr92-69-3

Englisch Name:4-Phenylphenol

CBNumberCB8197379

SummenformelC12H10O

Molgewicht170.21

MOL-Datei92-69-3.mol

Synonyma

Biphenyl-4-ol

Biphenyl-4-ol physikalisch-chemischer Eigenschaften

Schmelzpunkt	164-166 °C (lit.)
Siedepunkt	321 °C (lit.)
Dichte	1.0149 (rough estimate)
Dampfdruck	0Pa at 25℃
Brechungsindex	1.6188 (estimate)
Flammpunkt	330 °F
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	methanol: soluble50mg/mL, clear, colorless
Aggregatzustand	Flakes
pka	9.55(at 25℃)
Farbe	White to slightly yellow
PH	7 (0.7g/l, H2O, 20℃)
Wasserlöslichkeit	0.7 g/L (20 ºC)
Merck	14,7305
BRN	1907452
Stabilität	Stable. Incompatible with strong oxidizing agents, strong bases, halogens. Combustible.
LogP	3.6 at 25℃
CAS Datenbank	92-69-3(CAS DataBase Reference)
NIST chemische Informationen	p-Hydroxybiphenyl(92-69-3)
EPA chemische Informationen	4-Phenylphenol (92-69-3)

Sicherheit

Kennzeichnung gefährlicher	Xi,N
R-Sätze:	36/37/38-51/53-38
S-Sätze:	26-36/37-61-36
RIDADR	UN3077
WGK Germany	2
RTECS-Nr.	DV5850000
TSCA	Yes
HazardClass	9
PackingGroup	III
HS Code	29071900
Giftige Stoffe Daten	92-69-3(Hazardous Substances Data)
Toxizität	LD50 ipr-mus: 150 mg/kg NTIS** AD691-490

Gefahreninformationscode (GHS)

4-Phenylphenol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
R38:Reizt die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
light tan solid (odour threshold detection limit 0.7 ppm)
Verwenden
4-Phenylphenol is an intermediate for the production of varnish resins and nonionogenic emulsifiers which are used in the plant protection,polyurethane, and dyeing sectors.
Verwenden
Fluorescence and phosphorescence quantum yields and fluorescence and phosphorescence lifetimes were obtained for 4-phenylphenol adsorbed on filter paper with either NaCl, NaBr, or NaI at 296 and 93 K. The solid-surface fluorescence and phosphorescence quantum yield values and phosphorescence lifetime values were obtained for p-aminobenzoic acid (PABA) and 4-phenylphenol adsorbed on α-cyclodextrin/NaCl mixtures. 4-Phenylphenol is used as an antioxidant and is a potential EDC.
synthetische
4-phenylphenol synthesis: Add to a 50 ml round-bottom flask, in this order, 122 mg of phenylboronic acid, 414 mg of potassium carbonate, 220 mg of 4-iodophenol, and 10 ml of deionized water. Weigh in a suitably sized container 3 mg Pd on C 10%, add 1 ml of deionized water, and stir gently by hand to form a slurry that is then transferred to the reaction flask.

Couple the flask to a water-jacketed condenser, and reflux the mixture on a hot plate with a magnetic stirrer vigorously for 30 min (until a precipitate appears). After this time, switch off the plate and allow to cool to r.t. Add HCl 2 M to an acidic pH (check with indicator paper). Separate the resulting solid, still containing the catalyst, by filtering with a Hirsch funnel. Wash the solid with 10 ml of water. Then, in a Hirsch funnel, add 10 ml of MeOH, and collect the filtrate in a clean container. Add to the resulting MeOH solution 10 ml of deionized water to obtain the precipitate of the product. Purify by recrystallization, heating in a water bath container with the precipitate and the MeOH/H2O mixture. If necessary, add 1 to 2 ml more of hot MeOH, to finish dissolving the solid. Filter under vacuum with a Hirsch funnel, air dry the solid (can recover the next day). Weigh and calculate the yield.
Definition
ChEBI: 4-Phenylphenol is a member of the class of hydroxybiphenyls that is biphenyl carrying a hydroxy group at position 4.
Synthesis Reference(s)
Tetrahedron, 40, p. 4981, 1984 DOI: 10.1016/S0040-4020(01)91336-5
Tetrahedron Letters, 36, p. 125, 1995 DOI: 10.1016/0040-4039(94)02191-D
Allgemeine Beschreibung
4-Phenylphenol undergoes enzymatic polymerization and polymer developed is characterized by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. It is the intermediate in manufacture of 4-alkyl substituted phenol-formaldehyde resins.
Sicherheitsprofil
Acute poison by intraperitonealroute. Questionable carcinogen with experimentalcarcinogenic and tumorigenic data. When heated todecomposition it emits acrid, irritating fumes.
läuterung methode
Crystallise the phenol from aqueous EtOH, *C6H6, and dry it in a vacuum over CaCl2 [Buchanan et al. J Am Chem Soc 108 7703 1986]. [Beilstein 6 IV 4600.]

4-Phenylphenol Upstream-Materialien And Downstream Produkte

Biphenyl-4-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

92-69-3, 4-Phenylphenol Verwandte Suche:

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