Ro 314724

Ro 314724 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage matrix during chronic rheumatic diseases. Ro314724 displayed MMP-proteoglycanase inhibitory activity both in vitro and ex vivo and proved to be not harmful to the morphology, viability and proteoglycan biosynthesis of bovine articular cartilage explants.

Ro 314724 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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