lactosyl lysosphingolipid

lactosyl lysosphingolipid Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside G_M3. [Matreya, LLC. Catalog No. 2088]

• Verwenden

  Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column.

• Allgemeine Beschreibung

  Lactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract.

• Biochem/physiol Actions

  Lactosyl sphingosine?exhibits better hemolytic activity than lysolecithin.

lactosyl lysosphingolipid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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