Tixocortol

Tixocortol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Pivalone,Jouveinal,France,1978

• Verwenden

  Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.

• Definition

  ChEBI: A steroid sulfide in which the sulfanyl group is at C-21 of a polyoxygenated derivative of pregn-4-ene.

• Manufacturing Process

  In a reactor of 50 liters, sodium S-thiopivalate is prepared from 100 g of S_x0002_thiopivalic acid (0.844 mol), 214 cc of solution of sodium methylate, 3.95 M (0.844 mol) in 25 liters of anhydrous acetone.
  There are then added 285 g (0.603 mol) of dihydroxy-11β,17α-iodo-21-dioxo- 3,20-pregnene-4 and the mixture is brought up to the acetone reflux for two hours. The solvent is eliminated by distillation under vacuum until there is obtained a syrupy residue which is poured into 10 liters of iced water. The insoluble part is filtered and dried under vacuum.
  The crude product is purified by recrystallization from ethanol; weight: 250 g; yield: 89.5%.

• Therapeutic Function

  Antiinflammatory

Tixocortol Upstream-Materialien And Downstream Produkte

Tixocortol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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