3-O-Methylquercetin

Bezeichnung:3-O-Methylquercetin

CAS-Nr1486-70-0

Englisch Name:3-O-Methylquercetin

CBNumberCB81075557

SummenformelC16H12O7

Molgewicht316.26

MOL-Datei1486-70-0.mol

3-O-Methylquercetin physikalisch-chemischer Eigenschaften

Schmelzpunkt	275 °C
Siedepunkt	643.0±55.0 °C(Predicted)
Dichte	1.69±0.1 g/cm3(Predicted)
Löslichkeit	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Aggregatzustand	powder
pka	6.31±0.40(Predicted)
Farbe	Yellow
BRN	324509
Stabilität	Hygroscopic
LogP	2.020 (est)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	25
S-Sätze:	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

Gefahreninformationscode (GHS)

3-O-Methylquercetin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.
Verwenden
A metabolite of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells.
Definition
ChEBI: A tetrahydroxyflavone having the 4-hydroxy groups located at the 3'- 4'- 5- and 7-positions as well as a methoxy group at the 2-position.
Biologische Aktivität
3-O-Methylquercetin isolated from the herbs of Croton cascarilloides. It is a selective and competitive PDE3/PDE4 inhibitor,and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
Biochem/physiol Actions
3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
target
cAMP | PDE | IL Receptor | TNF-α | NOS | NO | Antifection

3-O-Methylquercetin Upstream-Materialien And Downstream Produkte

3-O-Methylquercetin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1486-70-0, 3-O-Methylquercetin Verwandte Suche:

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