Dichloracetonitril

Bezeichnung:Dichloracetonitril

CAS-Nr3018-12-0

Englisch Name:Dichloroacetonitrile

CBNumberCB7853456

SummenformelC2HCl2N

Molgewicht109.94

MOL-Datei3018-12-0.mol

Synonyma

Dichloracetonitril

Dichloracetonitril physikalisch-chemischer Eigenschaften

Siedepunkt	110-112 °C(lit.)
Dichte	1.369 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.44(lit.)
Flammpunkt	96 °F
storage temp.	0-6°C
Löslichkeit	soluble in Methanol
Farbe	Colorless to Light yellow to Light orange
Wichte	1.37
BRN	1739029
Expositionsgrenzwerte	NIOSH: IDLH 25 mg/m3
Stabilität	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS Datenbank	3018-12-0(CAS DataBase Reference)
IARC	3 (Vol. 52, 71) 1999
NIST chemische Informationen	Acetonitrile, dichloro-(3018-12-0)
EPA chemische Informationen	Dichloroacetonitrile (3018-12-0)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	10-22-34
S-Sätze:	26-36/37/39-45-25-16
RIDADR	UN 2920 8/PG 2
WGK Germany	3
RTECS-Nr.	AL8465000
F	9-19
HazardClass	3
PackingGroup	II
HS Code	29269090
Giftige Stoffe Daten	3018-12-0(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Dichloroacetonitrile Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R10:Entzündlich.
R22:Gesundheitsschädlich beim Verschlucken.
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S25:Berührung mit den Augen vermeiden.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
colourless liquid
Verwenden
Dichloroacetonitrile can be used as a reactant to prepare:
- Chiral α, α-dichloro-β-aminonitriles via Pd-catalyzed enantioselective Mannich-type reaction with imines.
- α, α-dialkyl-substituted nitriles by an alkylation reaction with trialkylboranes in the presence of phenoxide base as a base.
- Halogenated pyridines via copper-catalyzed reaction with methacrolein.
- α,α-dichloro-β-hydroxy nitriles by condensation reaction with aldehydes and ketones in the presence of an alkoxide base.
- Selenium heterocycle derivatives via Diels–Alder cyclization with selenoaldehydes.
- Dichloroacetonitrile can also be used to develop an efficient method for the extraction and determination of common volatile halogenated disinfection by-products using the static headspace technique coupled with gas chromatography-mass spectrometry.
Definition
ChEBI: Dichloroacetonitrile is an aliphatic nitrile.
Allgemeine Beschreibung
Clear liquid.
Air & Water Reaktionen
Burns slowly, emitting a thick black smoke, but will not flash . Water soluble.
Reaktivität anzeigen
Dichloroacetonitrile is a halogenated nitrile. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Dichloroacetonitrile emits toxic fumes of chlorine, cyanides and nitrogen oxides.
Brandgefahr
Dichloroacetonitrile is probably combustible.
Biochem/physiol Actions
Dichloroacetonitrile is direct-acting mutagen and induces DNA strand breaks in cultured human lymphoblastic cells. It induces apoptosis or necrosis in murine macrophage cell line via reactive oxygen intermediates-mediated oxidative mechanisms of cellular damage.
läuterung methode
Purify the nitrile by distillation or by gas chromatography. [Beilstein 2 IV 506.] FLAMMABLE.

Dichloroacetonitrile Upstream-Materialien And Downstream Produkte

Dichloracetonitril Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

3018-12-0, Dichloroacetonitrile Verwandte Suche:

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