CHMFL-KIT-033

CHMFL-KIT-033 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM[1]. IC50: 0.045 μM (c-KIT T670I mutant)[1]

• Einzelnachweise

  [1]. Liu X, et al. Discovery of ( E)- N1-(3-Fluorophenyl)- N3-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs). J Med Chem. 2019 May 23;62(10):5006-5024.

CHMFL-KIT-033 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(1)Suppliers