Methyl palmitate

Bezeichnung:Methyl palmitate

CAS-Nr112-39-0

Englisch Name:Methyl palmitate

CBNumberCB7783577

SummenformelC17H34O2

Molgewicht270.45

MOL-Datei112-39-0.mol

Methyl palmitate physikalisch-chemischer Eigenschaften

Schmelzpunkt	32-35 °C (lit.)
Siedepunkt	185 °C/10 mmHg (lit.)
Dichte	0.852 g/mL at 25 °C (lit.)
Dampfdruck	0.008Pa at 25℃
Brechungsindex	n20/D 1.4512(lit.)
Flammpunkt	>230 °F
storage temp.	2-8°C
Löslichkeit	Chloroform (Sparingly), Methanol (Slightly)
Aggregatzustand	Liquid or Low Melting Solid
Wichte	0.852
Farbe	Clear colorless
Geruch (Odor)	at 100.00 %. oily waxy fatty orris
Geruchsart	waxy
Wasserlöslichkeit	INSOLUBLE
BRN	1780973
LogP	7.38 at 36℃
CAS Datenbank	112-39-0(CAS DataBase Reference)
NIST chemische Informationen	Hexadecanoic acid, methyl ester(112-39-0)
EPA chemische Informationen	Methyl palmitate (112-39-0)

Sicherheit

S-Sätze:	22-24/25
WGK Germany	1
TSCA	Yes
HS Code	29157090
Giftige Stoffe Daten	112-39-0(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Methyl palmitate Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Clear colorless liquid or low melting solid. Soluble in alcohol, acetone, chloroform and benzene, soluble in ether, insoluble in water.
Verwenden
Methyl palmitate is used in the preparation of detergents, emulsifiers, wetting agents, stabilizers, resins, lubricants, plasticizers and animal feeds. It exhibits an anti-inflammatory and anti-fibrotic agent and prevents bleomycin-induced lung inflammation and fibrosis in rats. In addition, it also prevents carbon tetrachloride-induced liver fibrosis linked to reduce transforming growth factor beta, which is a secreted protein that controls proliferation, cellular differentiation and other functions in most cells.
Verwenden
Methyl palmitate can be used as an additive in food and cosmetic industries for the stabilization of fats and oil products by slowing down the auto-oxidation of unsaturated fatty acids.
Application
Methyl Palmitate is a fatty acid ester essential oil that naturally occurs in many plant species. Methyl Palmitate concentration in cells are known to be modulated by methanol. In experimental studies with isolated Kupffer cells, Methyl palmitate exhibited inhibitory activity towards phagocytosis and decreases cell viability.
Definition
ChEBI: Methyl palmitate is a fatty acid methyl ester. It has a role as a metabolite.
Biologische Funktion
Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long- term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake, and approximately 25% of the total plasma fatty acids in plasma lipoproteins. Saturated free fatty acids induce the expression of cyclooxygenase-2. Palmitic acid methyl ester (MP) is a fatty acid ester whose concentration in cells is modulated by methanol. In studies with isolated Kupffer cells, MP inhibits phagocytosis and decreases cell viability. In cells treated with lipopolysaccharide, it also decreases secretion of interleukin-10, TNF-α, nitric oxide, and prostaglandin E2. This effect is thought to occur by the inhibition of NF-κB.
Synthesis Reference(s)
Synthetic Communications, 16, p. 1423, 1986 DOI: 10.1080/00397918608056391
Allgemeine Beschreibung
Methyl palmitate (PAME), a fatty acid ester of palmitic acid, is a muscurinic receptors antagonist. Methyl palmitate functions as a vasodilator and relaxes the arterioles in retina upon electrical depolarization. In the superior cervical ganglion, methyl palmitate modulates nicotinic receptor. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. PAME activates Kv7 channels and promotes perivascular adipose tissue.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
Methyl palmitate has anti-inflammatory and anti-fibrotic effect. Methyl palmitate prevents bleomycin-induced lung inflammation and fibrosis in rats, by inhibiting NF-κB . Methyl palmitate also prevents CCl4-induced liver fibrosis linked to reduced TGF-β .

Methyl palmitate Upstream-Materialien And Downstream Produkte

Methyl palmitate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

112-39-0, Methyl palmitate Verwandte Suche:

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