Sulfobernsteinsäure-bis-2-ethylhexylester, Natrium-Salz Produkt Beschreibung

Dioctyl sulfosuccinate sodium salt Struktur
577-11-7
  • CAS-Nr.577-11-7
  • Bezeichnung:Sulfobernsteinsäure-bis-2-ethylhexylester, Natrium-Salz
  • Englisch Name:Dioctyl sulfosuccinate sodium salt
  • Synonyma:Docusatnatrium;Sulfobernsteinsäure-bis-2-ethylhexylester, Natrium-Salz
    AOT;DSS;sbo;DOSS;doxol;nevax;revac;OT-75;sv102;Wetter
  • CBNumber:CB7769467
  • Summenformel:C20H37O7S.Na
  • Molgewicht:444.56
  • MOL-Datei:577-11-7.mol
Sulfobernsteinsäure-bis-2-ethylhexylester, Natrium-Salz physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :173-179 °C(lit.)
  • Siedepunkt: :82.7°C
  • Dichte :1.1
  • storage temp.  :2-8°C
  • Löslichkeit :methanol: 0.1 M at 20 °C, clear, colorless
  • Aggregatzustand :Waxy Solid
  • Farbe :White
  • Wichte :1.005_PERCENT VOLATILE: 40
  • Wasserlöslichkeit :1.5 g/100 mL (25 ºC)
  • Sensitive  :Hygroscopic
  • maximale Wellenlänge (λmax) :λ: 260 nm Amax: 0.1
    λ: 280 nm Amax: 0.05
  • Merck  :14,3401
  • BRN  :4117588
  • Stabilität: :Stable. Combustible. Incompatible with strong oxidizing agents.
  • CAS Datenbank :577-11-7(CAS DataBase Reference)
  • EPA chemische Informationen :Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt(577-11-7)
Sicherheit

Dioctyl sulfosuccinate sodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden

  • R-Sätze Betriebsanweisung: R22:Gesundheitsschädlich beim Verschlucken.
    R38:Reizt die Haut.
    R41:Gefahr ernster Augenschäden.
    R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  • S-Sätze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
    S39:Schutzbrille/Gesichtsschutz tragen.
    S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  • Chemische Eigenschaften white solid, often supplied as an aqueous solution
  • Chemische Eigenschaften Docusate sodium is a white or almost white, waxlike, bitter tasting, plastic solid with a characteristic octanol-like odor. It is hygroscopic and usually available in the form of pellets, flakes, or rolls of tissuethin material.
  • Verwenden dioctyl sodium sulfosuccinate is a mild surfactant used as a cleans ing agent.
  • Verwenden Dioctyl sulfosuccinate sodium salt is a wetting and emulsifying agent that is slowly soluble in water, having a solubility of 1 g in 70 ml of water. It functions as a wetting agent in fumaric acid-containing powdered fruit drinks to help the acid dissolve in water. It is used as a stabilizing agent on gums at not more than 0.5% by weight of the gum. It is used as a flavor potentiator in canned milk where it improves and maintains the flavor of the sterilized milk during storage. It also functions as a processing aid in the manufacture of unrefined sugar. It is also termed sodium dioctylsulfosuccinate.
  • Verwenden Forms reverse micelles in hydrocarbon solvents; Suitable for the solubilization of the major myelin transmembrane proteolipid
  • Verwenden anticholinergic, treatment of motion sickness
  • Vorbereitung Methode Maleic anhydride is treated with 2-ethylhexanol to produce dioctyl maleate, which is then reacted with sodium bisulfite.
  • Trademarks Colace (Roberts Pharmaceutical); Correctol Stool Softener Laxative (Schering-Plough HealthCare); Dialose (Johnson & Johnson-Merck Consumer); Doxinate (Hoechst-Roussel); D-S-S (Parke-Davis); Modane Soft (Savage); Molofac (Bristol-Myers Squibb).
  • Allgemeine Beschreibung Odorless colorless to white waxy solid. Sinks and mixes slowly with water.
  • Air & Water Reaktionen Mixes slowly with water.
  • Reaktivität anzeigen Docusate sodium causes foaming and spreading of water. Assists in putting out fires by water. [USCG, 1999].
  • Health Hazard Liquid is strong irritant to eye and may irritate skin by removing natural oils. Ingestion causes diarrhea and intestinal bloating.
  • Brandgefahr Behavior in Fire: Causes foaming and spreading of water. Assists in putting out fires by water.
  • Pharmazeutische Anwendungen Docusate sodium and docusate salts are widely used as anionic surfactants in pharmaceutical formulations. Docusate sodium is mainly used in capsule and direct-compression tablet formulations to assist in wetting and dissolution.
  • Sicherheitsprofil Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. A skin and severe eye irritant. See also ESTERS. When heated to decomposition it emits toxic fumes of SOx and Na2O.
  • Sicherheit(Safety) Docusate salts are used in oral formulations as therapeutic agents for their fecal softening and laxative properties. As a laxative in adults, up to 500mg of docusate sodium is administered daily in divided doses; in children over 6 months old, up to 75 mg in divided doses is used. The quantity of docusate sodium used as an excipient in oral formulations should therefore be controlled to avoid unintended laxative effects. Adverse effects associated with docusate sodium include diarrhea, nausea, vomiting, abdominal cramps, and skin rashes. As with the chronic use of laxatives, the excessive use of docusate sodium may produce hypomagnesemia.
    Docusate salts are absorbed from the gastrointestinal tract and excreted in bile; they may cause alteration of the gastrointestinal epithelium. The gastrointestinal or hepatic absorption of other drugs may also be affected by docusate salts, enhancing activity and possibly toxicity. Docusate sodium should not be administered with mineral oil as it may increase the absorption of the oil.
    LD50 (mouse, IV): 0.06 g/kg
    LD50 (mouse, oral): 2.64 g/kg
    LD50 (rat, IP): 0.59 g/kg
    LD50 (rat, oral): 1.9 g/kg
  • Lager Docusate sodium is stable in the solid state when stored at room temperature. Dilute aqueous solutions of docusate sodium between pH 1–10 are stable at room temperature. However, at very low pH (<1) and very high pH (>10) docusate sodium solutions are subject to hydrolysis.
    The solid material is hygroscopic and should be stored in an airtight container in a cool, dry place.
  • läuterung methode Dissolve it in MeOH and the inorganic salts which precipitate are filtered off. Water is added and the solution is extracted several times with hexane. The residue is evaporated to one-fifth its original volume, *benzene is added and azeotropic distillation is continued until no water remains. The solvent is evaporated. The white residual solid is crushed and dried in vacuo over P2O5 for 48hours [El Seoud & Fendler J Chem Soc, Faraday Trans 1 71 452 1975]. [Beilstein 4 IV 114.] It solubilises major myelin trans membrane proteolipids, and forms reverse micelles in hydrocarbon solvents.
  • Inkompatibilitäten Electrolytes, e.g. 3% sodium chloride, added to aqueous solutions of docusate sodium can cause turbidity. However, docusate sodium possesses greater tolerance to calcium, magnesium, and other polyvalent ions than do some other surfactants. Docusate sodium is incompatible with acids at pH < 1 and with alkalis at pH > 10.
  • Regulatory Status GRAS listed. Included in the FDA Inactive Ingredients Database (IM injections; oral capsules, suspensions, and tablets; also topical formulations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Dioctyl sulfosuccinate sodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sulfobernsteinsäure-bis-2-ethylhexylester, Natrium-Salz Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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577-11-7, Dioctyl sulfosuccinate sodium salt Verwandte Suche:
  • Docusate sodium with Sodium benzoate
  • 2-ethylhexylsulfosuccinatesodium
  • aerosolgpg
  • aerosolot75
  • alcopolo
  • alphasolot
  • berol478
  • bis(2-ethylhexyl)s-sodiumsulfosuccinate
  • bis(ethylhexyl)esterofsodiumsulfosuccinicacid
  • AOT
  • (BIS-2-ETHYLHEXYL)SODIUM SULFOSUCCINATE
  • BIS(2-ETHYLHEXYL) SULFOSUCCINATE SODIUM SALT
  • BIS(2-ETHYLHEXYL) SULFOSUCCINIC ACID SODIUM SALT
  • BIS(2-ETHYLHEXYL) SULFOSUCEINATE, SODIUM SALT
  • DIOCTYL SODIUM SULFONSUCCINATE
  • DIOCTYL SODIUM SULFOSUCCINATE
  • DIOCTYL SULFOSUCCINATE
  • DIOCTYL SULFOSUCCINATE NA-SALT
  • 'DIOCTYL' SULFOSUCCINATE SODIUM SALT
  • DIOCTYL SULFOSUCCINATE, SODIUM SALT
  • DIOCTYL ESTER OF SODIUM SULPHOSUCCINIC ACID
  • DOCUSATE SODIUM
  • DOCUSATE SODIUM SALT
  • DOCUSATUM NATRICUM
  • DSS
  • DOSS
  • DI(2-ETHYLHEXYL) SULFOSUCCINATE SODIUM SALT
  • DI-2-ETHYLHEXYL SODIUM SULFOSUCCINATE
  • Diethylhexyl sulfosuccinate, sodium salt
  • Sulfosuccinic acid, di-(2-ethylhexyl) ester, sodium salt
  • Alpha-Sodium Sulfonate-di-Isooctanyl Succinate
  • Docusate
  • DOCUSATESODIUM,POWDER
  • BIS(2-ETHYLHEXYL)SULFOSUCCINATE(DOCUSATESODIUMSALT)
  • SULPHOSUCCINICACID,DIOCTYLESTER,SODIUMSALT
  • SUCCINICACID,SULPHO-1,4-BIS(2-ETHYLHEXYL)ESTER,SODIUMS.
  • SODIUMDI(2-ETHYLHEXYL)SULPHOSUCCINATE
  • Docusatnatrium
  • Bis(2-ethylhexyl)sulfosuccinate sodium
  • Dioctyl sodium sulfosuccinate: (Di-(2-ethylhexyl) sodium sulfosuccinate)
  • DIOCTYL SODIUM SULFUSUCCINATE
  • Wetter
  • Di(2-ethylhexyl) sulfosuccinic acid,sodium salt
  • Dioctyl sulfosuccinate sodium salt, AOT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Docusatum natricum, Sodium bis(2-ethylhexyl) sulfosuccinate, Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt, Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt
  • Dioctyl sulfosuccinate sodium salt, AOT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Sodium bis(2-ethylhexyl) sulfosuccinate, Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt, Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt
  • Dioctyl sulfosuccinate solution sodium salt
  • Dioctyl sulfosuccinate sodium salt, AOT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Docusate sodium salt, Sodium bis(2-ethylhexyl) sulfosuccinate, Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt, Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt
  • Bis(2-ethylhexyl) sulfosuccinate sodium salt, Docusate sodium
  • Dioctyl Sulfosuccinate Sodium Salt Sulfosuccinic Acid Bis(2-ethylhexyl) Ester Sodium Salt Docusate Sodium Salt
  • bis<(S)ethyl-2-hexyl> sodiuM sulfosuccinate
  • Aerosol O
  • Double(2-ethylhexyl)sulfosuccinate
  • Butanedioicacid, 2-sulfo-, 1,4-bis(2-ethylhexyl) ester, sodiuM salt (1:1)
  • Dioctyl sulfosuccinate sodiuM salt 98%
  • Docusate sodiuM salt puruM, >=96.0% (TLC)
  • Bis(2-ethylhexyl) Sulfosuccinate SodiuM Salt, 95.0%(T)
  • Docusate sodiuM SynonyMs Dioctylsulfosuccinate sodiuM salt
  • Dioctyl sulfosuccinate sodium salt solution