Dicyclanil

Bezeichnung:Dicyclanil

CAS-Nr112636-83-6

Englisch Name:Dicyclanil

CBNumberCB7743757

SummenformelC8H10N6

Molgewicht190.21

MOL-Datei112636-83-6.mol

Dicyclanil physikalisch-chemischer Eigenschaften

Siedepunkt	543.6±60.0 °C(Predicted)
Dichte	1.44±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
Löslichkeit	DMSO: 38 mg/mL (199.78 mM);Ethanol: 2 mg/mL (10.51 mM)
pka	4.09±0.50(Predicted)
Wasserlöslichkeit	Water: Insoluble
BRN	9265760
CAS Datenbank	112636-83-6(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn;N,N,Xn
R-Sätze:	20/22-51/53
S-Sätze:	36/37/39-61
RIDADR	UN 3077
WGK Germany	2

Gefahreninformationscode (GHS)

Dicyclanil Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Dicyclanil is an insect growth regulator belonging to the group of pyrimidinamines.
Dicyclanil is a pyrimidin derivative. Dicyclanil is an insect development inhibitor very specific for the prevention of blowfly strike in sheep. It does not control any other external parasites of sheep. It is used mainly as a spray-on. It is not used in other livestock, horses or pets.
Verwenden
Dicyclanil is a veterinary medication for the protection against early season myiasis.
Application
Dicyclanil may be used as an analytical reference standard for the quantification of the analyte in biological samples, bovine, porcine and chicken muscle using various chromatography techniques.
Pharmakokinetik
Dicyclanil has a long lasting action which interferes with moulting and pupation in dipteran species. However, the precise mode of action of this compound on ectoparasites is not known.
A variety of in vitro and in vivo pharmacodymanic tests were performed with dicyclanil in rats, mice and guinea pigs. In vitro, dicyclanil was devoid of significant effects on the neuromuscular junction at concentrations below 3 mM. Slight antagonistic effects on smooth muscle were reported at concentration levels above 0.1 mM. Dicyclanil caused a statistically significant increase in heart rate, tidal volume and minute volume at a dose level of 100 mg/kg bw in studies on the cardiovascular and respiratory systems in the rat. In various in vivo studies, dicyclanil was devoid of significant effects on behavior at a dose level of 1 mg/kg bw in mice.
Toxicity evaluation
Dicyclanil was investigated in a series of acute toxicity studies. The acute LD50 by the oral route in the rat was 520 mg/kg bw. The acute LD50 by the dermal route was greater than 2000 mg/kg bw in the rat. An acute inhalation toxicity study also conducted in the rat showed the acute LC50 to be 3,184 mg/m3 of air. The toxic effects were dyspnoea and reduced locomotor activity.

Dicyclanil Upstream-Materialien And Downstream Produkte

Dicyclanil Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

112636-83-6, Dicyclanil Verwandte Suche:

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