METHYL-D3-MALONIC ACID

Bezeichnung:METHYL-D3-MALONIC ACID

CAS-Nr42522-59-8

Englisch Name:METHYL-D3-MALONIC ACID

CBNumberCB7715949

SummenformelC4H3D3O4

Molgewicht121.11

MOL-Datei42522-59-8.mol

METHYL-D3-MALONIC ACID physikalisch-chemischer Eigenschaften

Schmelzpunkt	134-136 °C(lit.)
Flammpunkt	2 °C
storage temp.	-20°C
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
Farbe	White to Off-White

Sicherheit

Kennzeichnung gefährlicher	Xn,F
R-Sätze:	20/22-36/37/38-36-20/21/22-11
S-Sätze:	26-36-36/37-16
RIDADR	UN 1648 3 / PGII
WGK Germany	3

Gefahreninformationscode (GHS)

METHYL-D3-MALONIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White to Off-White Solid
Verwenden
An isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
Verwenden
Methyl-d3-malonic acid is an isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-depend ent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
Allgemeine Beschreibung
Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency.

METHYL-D3-MALONIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

42522-59-8, METHYL-D3-MALONIC ACID Verwandte Suche:

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