Dimethylcarbamoylchlorid

Bezeichnung:Dimethylcarbamoylchlorid

CAS-Nr79-44-7

Englisch Name:Dimethylcarbamoyl chloride

CBNumberCB7672462

SummenformelC3H6ClNO

Molgewicht107.54

MOL-Datei79-44-7.mol

Synonyma

Dimethylcarbamoylchlorid

Dimethylcarbamoylchlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	−33 °C(lit.)
Siedepunkt	167-168 °C775 mm Hg(lit.)
Dichte	1.168 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.453
Flammpunkt	155 °F
Löslichkeit	Chloroform (Soluble), DMSO (Sparingly)
Aggregatzustand	Liquid
pka	-1.85±0.70(Predicted)
Wichte	1.172
Farbe	Colorless to Yellow
Wasserlöslichkeit	Decomposes
Sensitive	Moisture Sensitive
BRN	878197
Expositionsgrenzwerte	ACGIH: TWA 0.005 ppm (Skin)
Stabilität	Moisture Sensitive
CAS Datenbank	79-44-7(CAS DataBase Reference)
IARC	2A (Vol. 12, Sup 7, 71) 1999
NIST chemische Informationen	Carbamic chloride, dimethyl-(79-44-7)
EPA chemische Informationen	Dimethylcarbamoyl chloride (79-44-7)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	45-22-23-36/37/38
S-Sätze:	53-45-99
RIDADR	UN 2262 8/PG 2
WGK Germany	3
RTECS-Nr.	FD4200000
F	9
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29241990
Giftige Stoffe Daten	79-44-7(Hazardous Substances Data)
Toxizität	A designated animal carcinogen (IARC) and hazardous waste (EPA); a suspected carcinogen in humans. It is a liquid boiling at 165_x0003_C that is used primarily in the manufacture of drugs and pesticides. Dimethyl carbamoyl chloride is extremely toxic.

Gefahreninformationscode (GHS)

Dimethylcarbamoyl chloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R22:Gesundheitsschädlich beim Verschlucken.
R23:Giftig beim Einatmen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Aussehen Eigenschaften
C3H6ClNO; (Chlorameisensäuredimethylamid).
Unangenehm stechend riechende, farblose bis gelbliche Flüssigkeit.
Gefahren für Mensch und Umwelt
Zersetzungsbeginn oberhalb 90^oC. Nur im Vakuum unzersetzt destillierbar. Zersetzungsprodukte NO_x , HCl. Korrosionswirkung auf Gebrauchsmetalle.
Verätzungen nach Augen- und Hautkontakt. Erblindungsgefahr! Nach Verschlucken Übelkeit und Erbrechen. Husten und Atemnot nach Einatmen. Inhalation kann Ödeme bewirken.
Kann Krebs erzeugen.
Schutzmaßnahmen und Verhaltensregeln
Gummihandschuhe (nur als kurzzeitiger Spritzschutz).
Verhalten im Gefahrfall
Mit Absorptionsmaterial, z.B. Rench-Rapid aufnehmen. Der Entsorgung zuführen.
Schaum, Kohlendioxid, Trockenlöschmittel.
Erste Hilfe
Nach Hautkontakt: Mit viel Wasser abwaschen. Abtupfen mit Polyethylenglycol 400 (Bereithalten).
Nach Augenkontakt: Mit viel Wasser bei geöffnetem Lidspalt mindestens 15 Minuten spülen. Augenarzt!
Nach Einatmen: Frischluft. Auxiloson-Spray (Bereithalten). Arzt!
Nach Verschlucken: Viel Wasser trinken, Erbrechen nicht herbeiführen. Sofort Arzt!
Nach Kleidungskontakt: Kontaminierte Kleidung sofort ausziehen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Als Sondermüll entsorgen.
Beschreibung
DMCC is a liquid. Molecularweight= 107.55; Specific gravity (H2O:1) 5 1.2; Boilingpoint= 165℃; Freezing/Melting point = 2 33℃; Vaporpressure = 2.5 mmHg at 25℃; Flash point = 68.3℃.Hazard Identification (based on NFPA-704 M RatingSystem): Health 3, Flammability 2, Reactivity 1 . Reactivewith water; decomposes.
Chemische Eigenschaften
Clear colorless liquid
Verwenden
Dimethylcarbamyl chloride is used to make dyes and pharmaceuticals.
Verwenden
As a chemical intermediate in the manufacture of carbamate drugs and pesticides
Verwenden
Dimethylcarbamoyl chloride has been used primarily as a chemical intermediate in the production of dyes, pharmaceuticals, pesticides, and rocket fuel (IARC 1999, HSDB 2009).
Definition
ChEBI: Dimethylcarbamoyl chloride is a halide. It is functionally related to a carbamic acid.
Allgemeine Beschreibung
A colorless to yellow liquid with a pungent odor. Burns to skin, eyes and mucous membranes. A lachrymator. Used to make dyes and pharmaceuticals.
Air & Water Reaktionen
Reacts with water or moisture in the air to form hydrochloric acid and dimethylcarbamic acid.
Reaktivität anzeigen
Dimethylcarbamoyl chloride is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Gives toxic fumes of NOx and HCl when burned [USCG, 1999].
Health Hazard
Material is extremely destructive to the mucous membranes, upper respiratory tract, eyes, and skin. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
Brandgefahr
Special Hazards of Combustion Products: Toxic fumes of NO x and HCl
Sicherheitsprofil
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal route. Moderately toxic by inhalation and ingestion. Human mutation data reported. Can cause skin and paplllary tumors by skin contact, and squamous cell carcinoma by inhalation. Will react with water or steam to produce toxic and corrosive fumes. A powerful lachrymator. When heated to decomposition it emits very toxic fumes of Cland NOx. See also CHLORIDES.
Toxikologie
The LD50 is 1170 mg/kg upon oral administration to rats and 350 mg/kg upon intraperitoneal administration to mice. The compound is irritating to the skin and eyes. All the test animals survived an 8-min inhalation test in an atmosphere saturated with vapors of the substance at 20℃. Longer exposure times led to death. No sensitization was observed in animal experiments.
mögliche Exposition
AgriculturalChemical; Tumorigen, Mutagen. DMCC is used as a chemical intermediate in the production of pharmaceuticals, pesticides, rocket fuel, and dye synthesis. Human exposure islimited to, but not restricted to, chemical workers, pesticideformulators, dye makers, and pharmaceutical workers.DMCC has been found at levels up to 6 ppm during the production of phthaloyl chlorides. It is possible that levels ofexposure might be higher in facilities in which the chemicalis used for further synthesis. When DMCC is used as a dyeintermediate, exposure can occur from the amount of residue in the product and its ability to migrate.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. If victim is conscious, administer water ormilk. Do not induce vomiting
Carcinogenicity
Dimethylcarbamoyl chloride is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Lager
(1) Color Code—White: Corrosive or ContactHazard; Store separately in a corrosion-resistant location.(2) Color Code—Blue: Health Hazard/Poison: Store in asecure poison location. Prior to working with DMCC youshould be trained on its proper handling and storage. Storein tightly closed containers in a cool, well-ventilated areaaway from strong oxidizers, strong acids, strong bases, andmoisture, since violent reactions can occur. Metal containers involving the transfer of this chemical should begrounded and bonded. Where possible, automatically pumpliquid from drums or other storage containers to processcontainers. Drums must be equipped with self-closingvalves, pressure vacuum bungs, and flame arresters. Useonly nonsparking tools and equipment, especially whenopening and closing containers of this chemical. Sources ofignition, such as smoking and open flames, are prohibitedwhere this chemical is used, handled, or stored in a mannerthat could create a potential fire or explosion hazard.Wherever this chemical is used, handled, manufactured, orstored, use explosion-proof electrical equipment and fittings. A regulated, marked area should be established wherethis chemical is handled, used, or stored in compliance withOSHA Standard 1910.1045.
Versand/Shipping
This compound requires a shipping label of“CORROSIVE.” It falls in Hazard Class 8 and PackingGroup II.
läuterung methode
It must be distilled under high vacuum to avoid decomposition. [Beilstein 4 IV 224.]
Inkompatibilitäten
Strong oxidizers; strong acids; strongbases. Reacts with water (rapidly hydrolyzes to carbondioxide, dimethylamine, dimethylcarbamic acid, and hydrochloric acid). Attacks metals in the presence of moisture.

Dimethylcarbamoyl chloride Upstream-Materialien And Downstream Produkte

Dimethylcarbamoylchlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

79-44-7, Dimethylcarbamoyl chloride Verwandte Suche:

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