5-Fluoroindole Struktur

5-Fluor-1H-indol

Bezeichnung:5-Fluor-1H-indol

CAS-Nr399-52-0

Englisch Name:5-Fluoroindole

CBNumberCB7445446

SummenformelC8H6FN

Molgewicht135.14

MOL-Datei399-52-0.mol

Synonyma

5-Fluor-1H-indol

5-Fluor-1H-indol physikalisch-chemischer Eigenschaften

Schmelzpunkt	45-48 °C (lit.)
Siedepunkt	120 °C / 1mmHg
Dichte	1.1203 (estimate)
Flammpunkt	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
pka	16.16±0.30(Predicted)
Aggregatzustand	Crystalline Powder
Farbe	Off-white
BRN	112350
InChI	InChI=1S/C8H6FN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
InChIKey	ODFFPRGJZRXNHZ-UHFFFAOYSA-N
SMILES	N1C2=C(C=C(F)C=C2)C=C1
CAS Datenbank	399-52-0(CAS DataBase Reference)
NIST chemische Informationen	1H-indole, 5-fluoro-(399-52-0)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
F	10
HazardClass	IRRITANT
HS Code	29339900

Gefahreninformationscode (GHS)

5-Fluoroindole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
off-white crystalline powder
Verwenden
- Reactant for preparation of 5-HT6 receptor ligands
- Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Reactant for preparation of antitumor agents
- Reactant for preparation of antibacterial agents
- Reactant for preparation of immunosuppressive agents
- Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
- Reactant for preparation of Myeloperoxidase Inhibitors
- Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors
Verwenden
• ;Reactant for preparation of 5-HT6 receptor ligands1• ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Reactant for preparation of antitumor agents3• ;Reactant for preparation of antibacterial agents4• ;Reactant for preparation of immunosuppressive agents5• ;Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes6• ;Reactant for preparation of Myeloperoxidase Inhibitors7• ;Reactant fo
Verwenden
5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.
Definition
ChEBI: An organofluorine compound that is the 5-fluoro derivative of indole.

5-Fluoroindole Upstream-Materialien And Downstream Produkte

5-Fluor-1H-indol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

399-52-0, 5-Fluoroindole Verwandte Suche:

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