ANTI-OCTAMER-BINDING TRANSCRIPTION FACTOR 4

ANTI-OCTAMER-BINDING TRANSCRIPTION FACTOR 4 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-POU5F1 (Oct4) antibody produced in rabbit has been used in Western Blotting.

• Biologische Aktivität

  POU class 5 homeobox 1 (POU5F1) may be a tumor initiating stem-like cell (TSC)-related marker. It has a role in stem cell pluripotency and self-renewal, and also modulates differentiation. The protein has been shown to be expressed in several cancers. POU5F1 is also vital for the induced pluripotent stem cell (iPSC) process.', 'POU5F1 or Oct4/Oct3 (Octamer-binding transcription factor), functions as an early developmental control gene. It has been recognized as fundamental in the maintenance of pluripotency in embryonic stem cells and in primordial germ cells. It is down regulated in all differentiated somatic cell types both in vivo and in vitro. This is being accomplished through increased DNA methylation and structural changes involving the immediate upstream regulatory region. POU5F1 serves as a marker for germ cell tumors (GCTs) eliciting pluripotentiality, especially including embryonal, seminoma/ dysgerminoma/ germinoma.

ANTI-OCTAMER-BINDING TRANSCRIPTION FACTOR 4 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(4)Suppliers