Guanosin-5'-(dinatriumdihydrogentriphosphat)

Bezeichnung:Guanosin-5'-(dinatriumdihydrogentriphosphat)

CAS-Nr56001-37-7

Englisch Name:Guanosine-5'-triphosphate disodium salt

CBNumberCB7261996

SummenformelC10H17N5NaO14P3

Molgewicht547.18

MOL-Datei56001-37-7.mol

Synonyma

Guanosin-5'-(dinatriumdihydrogentriphosphat)

Guanosin-5'-(dinatriumdihydrogentriphosphat) physikalisch-chemischer Eigenschaften

Schmelzpunkt	180°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
Löslichkeit	PBS (pH 7.2): 10 mg/ml
Aggregatzustand	Powder
Farbe	White
Wasserlöslichkeit	Soluble in water.
InChIKey	XIZYETZGWBYYEH-NGPBCCOENA-N
SMILES	O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=NC2C(NC(N)=NC1=2)=O)O.[NaH] \|&1:1,2,3,19,r\|
CAS Datenbank	56001-37-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-27-36/37/39-36
WGK Germany	3
F	10-21
HS Code	29349990

Gefahreninformationscode (GHS)

Guanosine-5'-triphosphate disodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signalling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration.
Chemische Eigenschaften
White crystalline powder
Verwenden
Guanosine 5?-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5?-Triphosphate, Disodium Salt is a phosphoryl donor in protein synthesis and in signal transduction.
Verwenden
A phosphoryl donor in protein synthesis and signal transduction
in vitro
Guanosine-5'-triphosphate disodium salt (500 μM, 24 hours) significantly promoted the upregulation of miR133a, miR133b, and myogenic regulatory factors Pax7, MyoD, and Myogenin in differentiated human myogenic precursor cells (MPCs).
Guanosine-5'-triphosphate disodium salt (5'-GTP trisodium salt) (500 μM, 24 h) can induce the release of exosomes from human myogenic progenitor cells.

Guanosin-5'-(dinatriumdihydrogentriphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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