1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC₅₀ = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC₅₀s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.

• Verwenden

  1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.

• Allgemeine Beschreibung

  1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.

• Biochem/physiol Actions

  Inhibitor of glycogen phosphorylase and α-glucosidases.

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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