3-Brompropionsure

Bezeichnung:3-Brompropionsure

CAS-Nr590-92-1

Englisch Name:3-Bromopropionic acid

CBNumberCB7177280

SummenformelC3H5BrO2

Molgewicht152.97

MOL-Datei590-92-1.mol

Synonyma

3-Brompropionsure

3-Brompropionsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	58-62 °C(lit.)
Siedepunkt	140-142 °C (45 mmHg)
Dichte	1.48 g/mL at 25 °C(lit.)
Brechungsindex	1.4753 (estimate)
Flammpunkt	150 °F
storage temp.	2-8°C
Löslichkeit	H₂O: 0.1 g/mL, clear
Aggregatzustand	Crystals or Crystalline Powder
pka	4.00(at 25℃)
Farbe	White to slightly yellow
Wasserlöslichkeit	0.1 g/mL
Merck	14,1433
BRN	1071333
Dielectric constant	11.0（20℃）
CAS Datenbank	590-92-1(CAS DataBase Reference)
NIST chemische Informationen	Propanoic acid, 3-bromo-(590-92-1)
EPA chemische Informationen	Propanoic acid, 3-bromo- (590-92-1)

Sicherheit

Kennzeichnung gefährlicher	F,C
R-Sätze:	11-34
S-Sätze:	26-36/37/39-45
RIDADR	UN 3261 8/PG 2
WGK Germany	3
RTECS-Nr.	UE7875000
Hazard Note	Corrosive/Highly Flammable
TSCA	Yes
HazardClass	4.1
PackingGroup	III
HS Code	29159080
Giftige Stoffe Daten	590-92-1(Hazardous Substances Data)

Gefahreninformationscode (GHS)

3-Bromopropionic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
white to pale yellow or orange crystalline. soluble in water, alcohol, ether, chloroform, benzene. Hydrolysis in alkaline solution generates hydroxypropionic acid. Corrosive. for organic synthesis.
Verwenden
3-Bromopropionic acid used as quaternization agent in amperometric biosensors.
Application
3-Bromopropionic acid is a widely used chemical intermediate. It can be used as a starting material to synthesize derivatives such as esters, acid halides and amides; the active group bromine can undergo a series of reactions, and is mainly used in the fields of pesticides and medicines. Such as the pesticides diflufenacil, furalax and so on.
synthetische
3-Bromopropionic acid is prepared by reacting acrylonitrile with hydrogen bromide to obtain bromopropionitrile and then hydrolyzing it. Add acrylonitrile to boiling hydrobromic acid, reflux at 130°C for 6 hours, extract the solid obtained by filtration with ethanol, and obtain the crude product after recovering ethanol by distillation under reduced pressure. By heating 2-cyanoethanol and 40% hydrobromic acid to reflux for 2h, 3-bromopropionic acid can also be produced with a yield of over 80%.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 2807, 1949 DOI: 10.1021/ja01176a061
Organic Syntheses, Coll. Vol. 1, p. 131, 1941
Sicherheitsprofil
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.
läuterung methode
The acid crystallises as plates from CCl4. It is soluble in organic solvents and H2O. Its methyl ester has b 65o/18mm and 80o/27mm. The S-benzylisothiouronium salt has m 136o. [Kendall & McKenzie Org Synth Coll Vol I 131 1941, Beilstein 2 IV 764.]

3-Bromopropionic acid Upstream-Materialien And Downstream Produkte

3-Brompropionsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

590-92-1, 3-Bromopropionic acid Verwandte Suche:

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