Methylbromacetat

Bezeichnung:Methylbromacetat

CAS-Nr96-32-2

Englisch Name:Methyl bromoacetate

CBNumberCB7171783

SummenformelC3H5BrO2

Molgewicht152.97

MOL-Datei96-32-2.mol

Synonyma

Methylbromacetat

Methylbromacetat physikalisch-chemischer Eigenschaften

Schmelzpunkt	-50°C
Siedepunkt	51-52 °C/15 mmHg (lit.)
Dichte	1.616 g/mL at 25 °C (lit.)
Dampfdruck	18 hPa (50 °C)
Brechungsindex	n20/D 1.458(lit.)
Flammpunkt	145 °F
storage temp.	Store below +30°C.
Aggregatzustand	Liquid
Wichte	1.416
Farbe	Clear colorless to slightly yellow
Wasserlöslichkeit	Miscible with methanol, ether and acetone. Slightly miscible with water
FreezingPoint	<-50℃
BRN	506256
LogP	0.71 at 25℃
CAS Datenbank	96-32-2(CAS DataBase Reference)
NIST chemische Informationen	Acetic acid, bromo-, methyl ester(96-32-2)
EPA chemische Informationen	Acetic acid, bromo-, methyl ester (96-32-2)

Sicherheit

Kennzeichnung gefährlicher	T,Xi,F
R-Sätze:	25-34-37-23/24/25-40-36/37/38-38
S-Sätze:	26-36/37/39-45-28A-36-16
RIDADR	UN 2643 6.1/PG 2
WGK Germany	3
RTECS-Nr.	AF6300000
F	19
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29159080
Giftige Stoffe Daten	96-32-2(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Methyl bromoacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R34:Verursacht Verätzungen.
R37:Reizt die Atmungsorgane.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Colorless liquid
Verwenden
Methyl bromoacetate is used in the synthesis of coumarins and cis-cyclopropanes. It reacts with the conjugate base of (methylmethoxycarbene)pentacarbonylchromium(0) to prepare alkylated carbene complexes. Further, it is used to make vitamins and pharmaceuticals.
Verwenden
Methyl bromoacetate was used in the synthesis of novel coumarins. It was also employed in the synthesis of cis-cyclopropanes
Application
Methyl Bromoacetate is an organic building block that has been used as a reactant in the preparation of isoquinolinone indole acetic acid derivatives as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseases.
Allgemeine Beschreibung
A colorless to straw-colored liquid with a sharp penetrating odor. Denser than water and soluble in water. Severly irritates skin and eyes. Toxic by ingestion and inhalation. Used to make vitamins and pharmaceuticals.
Air & Water Reaktionen
Highly flammable. Soluble in water.
Reaktivität anzeigen
Methyl bromoacetate is a halogenated ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Hazard
Vapor is strong irritant to eyes.
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Brandgefahr
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Sicherheitsprofil
Poison by intravenous route. When heated to decomposition it emits toxic fumes of Br-. See also ESTERS.

Methyl bromoacetate Upstream-Materialien And Downstream Produkte

Methylbromacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

96-32-2, Methyl bromoacetate Verwandte Suche:

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