Tripelennaminhydrochlorid

Bezeichnung:Tripelennaminhydrochlorid

CAS-Nr154-69-8

Englisch Name:TRIPELENNAMINE HYDROCHLORIDE

CBNumberCB7126697

SummenformelC16H22ClN3

Molgewicht291.82

MOL-Datei154-69-8.mol

Synonyma

Tripelennaminhydrochlorid

Tripelennaminhydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	192-193℃
Dichte	1.20
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	DMSO : 25 mg/mL (85.67 mM; Need ultrasonic)
EPA chemische Informationen	Tripelennamine hydrochloride (154-69-8)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-36/37/38
S-Sätze:	26-36
WGK Germany	3
RTECS-Nr.	US3150000
HS Code	2933399090
Toxizität	LD50 in mice (mg/kg): 47 i.p. (Walker)

Gefahreninformationscode (GHS)

TRIPELENNAMINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Solid
Verwenden
Tripelennamine is a first-generation antihistamine, used in the treatment of asthma, hay fever, and urticaria.
Verwenden
antihistaminic;histamine H1 antagonist
Trademarks
PBZ (Novartis).
Allgemeine Beschreibung
Tripelennamine hydrochlorideis a white crystalline powder that darkensslowly on exposure to light. The salt is soluble in water(1:0.77) and in alcohol (1:6). It has a pKa of about 9, and a0.1% solution has a pH of about 5.5.
Tripelennamine, the first ethylenediamine developed inthe United States and is well absorbed when given orally. Itappears to be as effective as diphenhydramine and may havethe advantage of fewer and less severe side reactions.Drowsiness may occur, however, and may impair the abilityto perform tasks requiring alertness. The concurrent use ofalcoholic beverages should be avoided.
Allgemeine Beschreibung
Odorless white crystalline powder or solid. Bitter taste. Solutions are neutral to litmus. pH of aqueous solution (25 mg/mL): 6.71. pH of aqueous solution (50 mg/mL): 6.67. pH of aqueous solution (100 mg/mL): 5.56.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
TRIPELENNAMINE HYDROCHLORIDE behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Brandgefahr
Flash point data for TRIPELENNAMINE HYDROCHLORIDE are not available; however, TRIPELENNAMINE HYDROCHLORIDE is probably combustible.
Veterinary Drugs and Treatments
Antihistamines are used in veterinary medicine to reduce or help prevent histamine mediated adverse effects. Tripelennamine has been used as a CNS stimulant in “Downer cows” when administered slow IV.

Tripelennaminhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

154-69-8, TRIPELENNAMINE HYDROCHLORIDE Verwandte Suche:

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