IGF-1 LR3
Bezeichnung:IGF-1 LR3
CAS-Nr946870-92-4
Englisch Name:IGF-1 LR3
CBNumberCB6947862
Molgewicht0
MOL-DateiMol file
IGF-1 LR3 Chemische Eigenschaften,Einsatz,Produktion Methoden
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Beschreibung
Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1). -
Verwenden
The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours). -
benefits
Based on the literature, IGF1-LR3 has been shown to:
Increase Fat Loss
Aid in the development of lean muscle mass
Add protection against muscle wasting
Reduce inflammation -
Nebenwirkungen
Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers.
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