4-Hydroxy-2-pyridon

Bezeichnung:4-Hydroxy-2-pyridon

CAS-Nr626-03-9

Englisch Name:2,4-Dihydroxypyridine

CBNumberCB6746357

SummenformelC5H5NO2

Molgewicht111.1

MOL-Datei626-03-9.mol

Synonyma

4-Hydroxy-2-pyridon

4-Hydroxy-2-pyridon physikalisch-chemischer Eigenschaften

Schmelzpunkt	272-276 °C (lit.)
Siedepunkt	208.19°C (rough estimate)
Dichte	1.3113 (rough estimate)
Brechungsindex	1.4260 (estimate)
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	DMSO, Methanol
Aggregatzustand	powder
pka	pK1:1.37(+1);pK2:6.45(0);pK3:13(+1) (20°C)
Farbe	light yellow
Wasserlöslichkeit	6.211g/L(20 ºC)
BRN	108533
InChI	InChI=1S/C5H5NO2/c7-4-1-2-6-5(8)3-4/h1-3H,(H2,6,7,8)
InChIKey	ZEZJPIDPVXJEME-UHFFFAOYSA-N
SMILES	C1(=O)NC=CC(O)=C1
CAS Datenbank	626-03-9(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37/39
WGK Germany	3
RTECS-Nr.	UV1146800
HazardClass	IRRITANT
HS Code	29339900

Gefahreninformationscode (GHS)

2,4-Dihydroxypyridine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Application
2,4-Dihydroxypyridine is profusely employed in multiple fields such as pesticide design, pharmacology, and clinical therapeutics[1]. This compound could used as a new growth-directing agent to to prepare AgPt nanorings supported on reduced graphene oxide (AgPt NRs-rGO) through a facile one-pot wet-chemical route. This label-free electrochemical immunosensor could be used for the sensitive detection of CEA[2].
Beschreibung
2,4-Dihydroxypyridine belongs to the class of organic compounds known as pyridinones. Pyridinones are compounds containing a pyridine ring, which bears a ketone. This compound has been identified in human blood. 2,4-dihydroxypyridine is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically 2,4-Dihydroxypyridine is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.
Chemische Eigenschaften
white to yellow-beige crystals or cryst. powder
Verwenden
2,4-Dihydroxypyridine (3-deazauracil) was used in the synthesis of diazaphenoxathiin skeleton.
Definition
ChEBI: 2,4-Dihydroxypyridine is a pyridone.
Allgemeine Beschreibung
2,4-Dihydroxypyridine (3-deazauracil) is a potent inhibitor of dihydrouracil dehydrogenase.
Einzelnachweise
[1] Pajares A, et al. Ionization effects on the sensitized photooxidation of 2,3-dihydroxypyridine and 2,4-dihydroxypyridine: a kinetic study. Journal of Photochemistry and Photobiology A: Chemistry, 2002; 153: 101-107.
[2] Wang R, et al. A label-free electrochemical immunosensor based on AgPt nanorings supported on reduced graphene oxide for ultrasensitive analysis of tumor marker. Sensors and Actuators B: Chemical, 2017; 254: 1174-1181.

2,4-Dihydroxypyridine Upstream-Materialien And Downstream Produkte

4-Hydroxy-2-pyridon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

626-03-9, 2,4-Dihydroxypyridine Verwandte Suche:

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