2-Chlor-1-oxo-ethan

Bezeichnung:2-Chlor-1-oxo-ethan

CAS-Nr107-20-0

Englisch Name:Chloroacetaldehyde

CBNumberCB6676908

SummenformelC2H3ClO

Molgewicht78.5

MOL-Datei107-20-0.mol

Synonyma

Chloracetaldehyd

2-Chlor-1-oxo-ethan

2-Chloracetaldehyd

2-Chlor-1-oxo-ethan physikalisch-chemischer Eigenschaften

Schmelzpunkt	-28--23°C
Siedepunkt	80-100 °C(lit.)
Dichte	1.236 g/mL at 25 °C
Dampfdruck	100 at 20 °C (NIOSH, 1997)
Brechungsindex	n20/D 1.407
Flammpunkt	128 °F
Löslichkeit	Soluble in ether (Weast, 1986), acetone, and methanol (Hawley, 1981)
Aggregatzustand	Colorless liquid
Wasserlöslichkeit	soluble in acetone, methanol. Fully miscible in water.
Sensitive	Air Sensitive
Merck	2109
BRN	1071226
Expositionsgrenzwerte	Ceiling 3 mg/m³ (1 ppm) (ACGIH); IDLH.
LogP	0.62 at 25℃ and pH5.8
CAS Datenbank	107-20-0(CAS DataBase Reference)
NIST chemische Informationen	Acetaldehyde, chloro-(107-20-0)
EPA chemische Informationen	Chloroacetaldehyde (107-20-0)

Sicherheit

Kennzeichnung gefährlicher	T+,N
R-Sätze:	24/25-26-34-40-50-35
S-Sätze:	26-28-36/37/39-45-61
RIDADR	UN 2232 6.1/PG 1
OEL	Ceiling: 1 ppm (3 mg/m3)
WGK Germany	-
RTECS-Nr.	AB2450000
TSCA	Yes
HazardClass	6.1(a)
PackingGroup	I
HS Code	29130000
Giftige Stoffe Daten	107-20-0(Hazardous Substances Data)
Toxizität	Acute oral LD₅₀ for rats 75 mg/kg, mice 69 mg/kg (quoted, RTECS, 1985).
IDLA	45 ppm

Gefahreninformationscode (GHS)

Chloroacetaldehyde Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
KLARE FARBLOSE FLüSSIGKEIT MIT STECHENDEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die Dämpfe sind schwerer als Luft.
CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen unter Bildung giftiger Rauche mit Chlor. Reagiert mit Oxidationsmitteln und Säuren unter Explosionsgefahr.
ARBEITSPLATZGRENZWERTE
TLV: 1 ppm (als STEL, ceiling); (ACGIH 2005).
MAK: Hautresorption; Krebserzeugend Kategorie 3B; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation der Dämpfe und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C kann sehr schnell eine gesundheitsschädliche Kontamination der Luft eintreten.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
ätzend. Der Dampf verätzt die Augen, die Haut und die Atemwege. Inhalation hoher Dampfkonzentrationen kann zu Lungenödem führen (s.Anm.). Die Auswirkungen treten u.U. verzögert ein. ärztliche Beobachtung notwendig. (s.Anm.)
LECKAGE
Gefahrenbereich verlassen! Fachmann zu Rate ziehen! Belüftung. Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit viel Wasser wegspülen. Persönliche Schutzausrüstung: Vollschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät.
R-Sätze Betriebsanweisung:
R24/25:Giftig bei Berührung mit der Haut und beim Verschlucken.
R26:Sehr giftig beim Einatmen.
R34:Verursacht Verätzungen.
R40:Verdacht auf krebserzeugende Wirkung.
R50:Sehr giftig für Wasserorganismen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
oroacetaldehyde is a combustible, color?less liquid with a very sharp, irritating odor. Molecularweight=78.50; Specific gravity (H2O:1)=1.19 (40%solution); Boiling point=85 100℃; Freezing/Meltingpoint=16℃(40% solution); Vapor pressure 5100 mmHg at 20℃; Flash point=87.7℃(40%626 Chloroacetaldehydesolutions). Hazard Identification (based on NFPA 704 MRating System): Health 3, Flammability 2, Reactivity 0(able to polymerize on standing). Soluble in water.
Chemische Eigenschaften
Chloroacetaldehyde is a combustible, colorless liquid with a very sharp, irritating odor.
Physikalische Eigenschaften
Clear, colorless liquid with an irritating, acrid odor
Verwenden
In the manufacture of 2- aminothiazole; to facilitate bark removal from tree trunks; formed during the chlorination of drinking water; a metabolite of vinyl chloride
Verwenden
Chloroacetaldehyde is used in the productionof 2-aminothiazole.
Definition
ChEBI: Chloroacetaldehyde is acetaldehyde substituted at C-2 by chlorine. It derives from an acetaldehyde.
Allgemeine Beschreibung
A clear colorless liquid with a pungent odor. Flash point about 190°F. Corrosive to skin and mucous membranes. Chloroacetaldehyde is very toxic by inhalation.
Air & Water Reaktionen
Soluble in water. Forms an insoluble hemihydrate at greater than 50% concentration.
Reaktivität anzeigen
Chloroacetaldehyde polymerizes on standing. At greater than 50% concentration in water, Chloroacetaldehyde forms an insoluble hemihydrate. Sensitive to heat. Reacts with oxidizing agents. Incompatible with acids and water . Burns to give poisonous and irritating gases.
Hazard
Corrosive to skin and mucous membranes. TLV: ceiling 1 ppm.
Health Hazard
Chloroacetaldehyde is a highly toxic andcorrosive compound that can injure the eyes,skin, and respiratory system. Exposure toits vapor at high concentrations can producesevere irritation and impair vision. At lowconcentrations, the vapor can cause irritationand sore eyelids. Brief contact with 40%aqueous solution can result in skin burn anddestruction of tissues. A 0.5% dilute solutioncan still be irritating on skin.
Inhalation of its vapor at the 5-ppm levelcan irritate the eyes, nose, and throat. Ingestionmay result in pulmonary edema. Swallowinga concentrated solution may be fatal.The acute toxicity data are as follows:
LD50 value, intraperitoneal (rats): 2 mg/kg
LD50 value, oral (rats): 23 mg/kg
LD50 value, skin (rabbits): 67 mg/kg
This compound is a mutagen, testing positivein the Ames test.
Brandgefahr
Combustible; flash point (closed cup) 87.8°C (190°F); flash point of 50% aqueous solution 53°C (128°F) (at this concentration it may form insoluble hemihydrate); it forms an explosive mixture with air. Reactions with strong acids and oxidizers are exothermic.
Sicherheitsprofil
Suspected carcinogen. Poison by ingestion, skin contact, and intraperitoneal routes. Mutation data reported. Combustible when exposed to heat or flame. Reacts with oxidizing materials. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of Cl-. See also ALDEHYDES and CHLORIDES.
mögliche Exposition
Chloroacetaldehyde is used as a fungicide; as an intermediate in 2-aminothiazole manufacture; and in bark removal from tree trunks.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least30 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24-48 h afterbreathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a corticosteroid spray.
Carcinogenicity
Chloroacetaldehyde has been reported to be an inhibitor of DNA synthesis and to form DNA adducts; it is mutagenic in Salmonella typhimurium and in Chinese hamster cells.
Limited in vivo genotoxicity studies with chloroacetaldehyde were negative.
Environmental Fate
Chemical/Physical. Polymerizes on standing (Windholz et al., 1983).
Lager
Polymerizable upon standing. Color Code—Blue:Health Hazard/Poison: Store in a secure poison location.Prior to working with chloroacetaldehyde you should betrained on its proper handling and storage. Store in tightlyclosed containers in a cool, dry, well-ventilated area. Metalcontainers involving the transfer of this chemical should begrounded and bonded. Where possible, automatically pumpliquid from drums or other storage containers to processcontainers. Drums must be equipped with self-closingvalves, pressure vacuum bungs, and flame arresters. Useonly nonsparking tools and equipment, especially whenopening and closing containers of this chemical. Sources ofignition, such as smoking and open flames, are prohibitedwhere this chemical is used, handled, or stored in a mannerthat could create a potential fire or explosion hazard.
Versand/Shipping
UN22322-Chloroethanal, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, Inhalation Hazard Zone B.
Inkompatibilitäten
Heat and water sensitive; concentrations of .50% form insoluble hemihydrate material on contact with water. Reacts with oxidizers, acids. On heating,chloroacetaldehyde releases chlorine fumes. Polymerizable upon standing
Waste disposal
Incineration, preferably after mixing with another combustible fuel; care must be exercised to assure complete combustion to prevent the formation of phosgene; an acid scrubber is necessary to remove the halo acids produced.

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