2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID

2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC₅₀s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of Δ⁹-tetrahydrocannabinol (Δ⁹-THC).

• Verwenden

  N-Arachidonoyltaurine is a polyunsaturated lipid that inhibits the Cav3.3 current in T-type calcium channels.

• Definition

  ChEBI: A fatty acid-taurine conjugate derived from arachidonic acid.

2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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