4-Fluoracetophenon

Bezeichnung:4-Fluoracetophenon

CAS-Nr403-42-9

Englisch Name:4-Fluoroacetophenone

CBNumberCB6419110

SummenformelC8H7FO

Molgewicht138.14

MOL-Datei403-42-9.mol

Synonyma

4-Fluoracetophenon

4-Fluoracetophenon physikalisch-chemischer Eigenschaften

Schmelzpunkt	4 °C
Siedepunkt	77-78 °C10 mm Hg(lit.)
Dichte	1.143 g/mL at 20 °C(lit.)
Brechungsindex	n20/D 1.511(lit.)
Flammpunkt	160 °F
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform, Ethyl Acetate
Aggregatzustand	Liquid
Wichte	1.138
Farbe	Clear colorless to slightly yellow
BRN	386013
InChIKey	ZDPAWHACYDRYIW-UHFFFAOYSA-N
CAS Datenbank	403-42-9(CAS DataBase Reference)
NIST chemische Informationen	Ethanone, 1-(4-fluorophenyl)-(403-42-9)
EPA chemische Informationen	4'-Fluoroacetophenone (403-42-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-23
WGK Germany	3
TSCA	T
HazardClass	IRRITANT
HS Code	29147090

Gefahreninformationscode (GHS)

4-Fluoroacetophenone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
Chemische Eigenschaften
Clear colorless to slightly yellow liquid
Verwenden
4’Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.
Verwenden
4’-Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.
Verwenden
4-Fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthese

General procedure: Oximes (1.0 mmol), Amberlyst-15 (0.02 g), FPA53-NO2(0.02 g), and solvent (1.5 mL) were introduced into a 25-cm-high, 90-mL autoclave with a glass tube inside equipped with magnetic stirrer (Scheme 2). Then the autoclave was charged with oxygen to 0.1 MPa. The reaction mixture was stirred at desirable temperature for special time. Progress of the reaction was monitored by thin-layer chromatography (TLC) or gas chromatography (GC). After the reaction, the resin (Amberlyst-15 and FPA53-NO2) was separated from the reaction mixture by filtration and extracted with 3 mL CH3CN (2 1.5 ml). The solvent was removed under reduced pressure. The residue was further purified by column chromatography on silica gel (300 mesh) with hexane/ethyl acetate to give the corresponding carbonyl compounds.

4-Fluoroacetophenone Upstream-Materialien And Downstream Produkte

4-Fluoracetophenon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

403-42-9, 4-Fluoroacetophenone Verwandte Suche:

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