ANTI-FOLLICLE STIMULATING HORMONE, HUMAN

ANTI-FOLLICLE STIMULATING HORMONE, HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-Follicle-Stimulating Hormone Receptor antibody produced in rabbit has also been used in immunohistochemistry in ovine and reproductive tissues. It has also been used in western blotting.

• Allgemeine Beschreibung

  Follicle stimulating hormone receptor (FSHR) belongs to the G protein-coupled receptors family and is a glycoprotein. FSHR gene is mapped to human chromosome 2p16.3. FSHR comprises hydrophilic domain, hydrophobic membrane regions, C-terminal extracellular domain, and short intracellular domain.

• Biochem/physiol Actions

  Follicle stimulating hormone receptor (FSHR) is located on Sertoli cells of the testes and the granulosa cells of ovary. The pituitary glycoprotein hormone, FSH, binds to FSHR and regulates the function of gonads and overall fertility. In Sertoli cells, FSHR-mediated cell proliferation determines the spermatogenic output. In ovarian granulosa cells, FSHR signaling mediates follicular growth and maturation of oocytes. Polymorphisms in the FSHR is implicated in premature ovarian insufficiency.

ANTI-FOLLICLE STIMULATING HORMONE, HUMAN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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