"Desloratadine Citrate Disodium"

"Desloratadine Citrate Disodium" Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Desloratadine (Loratadine EP Impurity D; Loratadine USP Related Compound A) is an active metabolite of Loratadine (L469575) and used as an oral non-sedating antihistamine to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria (1,2,3).

• Clinical Use

  Antihistamine:
  Symptomatic relief of allergy such as hay fever, urticaria

• Arzneimittelwechselwirkung

  Potentially hazardous interactions with other drugs
  Antivirals: concentration possibly increased by ritonavir.

• Stoffwechsel

  Desloratadine is the primary active metabolite of loratadine. Approximately 40% of the dose is excreted in the urine and 42% in the faeces over a 10 day period and mainly in the form of conjugated metabolites. Approximately 27% of the dose is eliminated in the urine during the first 24 hours. Less than 1% of the active substance is excreted unchanged in the active form, as desloratadine.

"Desloratadine Citrate Disodium" Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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